New Cardiac Imaging Tools and Invasive Techniques in Systemic Autoimmune Diseases (Part II)

M. Corda, M. Porcu, F. Atzeni, L. Gianturco, P. Sarzi-Puttini, M. Turiel

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Systemic inflammatory diseases are associated with an increase in cardiovascular (CV) morbidity and mortality. CV involvement in systemic inflammatory diseases is highly heterogeneous, with manifestations affecting different heart structures. New instruments now allow an early diagnosis and prompt treatment. Over the last few years, Cardiac MRI has emerged as a noninvasive means of accurately and reproducibly assessing myocardial anatomy and function and has become the gold standard for measuring the ejection fraction, and left and right ventricular volumes. It can reveal myocardial lesions in patients with mixed connective tissue disease (CTD) and cardiac symptoms, including myocardial infarction, inflammation, and widespread subendocardial fibrosis and perfusion defects, which require further cardiac investigation and/or treatment. Computed tomography (CT) has evolved into such a potent means of diagnosis. It has become very important for cardiologists because it is widely available, easy to use, noninvasive, and highly sensitive in detecting coronary artery disease, and evaluating pericardial disease, pericardial fluid, and pericardial neoplasms. Radiation doses are a matter of concern and special measures need to be taken to avoid unnecessarily high doses when CT is used for coronary artery imaging. Pulmonary arterial hypertension (PAH) is one of the major complications of CTDs such as systemic sclerosis, systemic lupus erythematosus, and mixed CTD. Right heart catheterization is a fundamental means of confirming a diagnosis of PAH and assessing a risk that, when performed at dedicated centers, is associated with low morbidity and mortality rates. Myocarditis is an inflammatory disease of the myocardium caused by various infectious and noninfectious triggers. Systemic autoimmune diseases such as Churg–Strauss syndrome or hypereosinophilic syndrome (Loeffler's disease) can be associated with eosinophilic myocarditis. In the case of cardiac sarcoidosis and giant cell myocarditis, which are rare causes of inflammatory myocardial disease, early diagnosis and treatment significantly improve prognosis. The diagnostic gold standard is still an endomyocardial biopsy.

Original languageEnglish
Title of host publicationHandbook of Systemic Autoimmune Diseases
PublisherElsevier Ltd
Pages209-226
Number of pages18
Volume14
DOIs
Publication statusPublished - Jan 1 2017

Publication series

NameHandbook of Systemic Autoimmune Diseases
Volume14
ISSN (Print)1571-5078

Fingerprint

Autoimmune Diseases
Myocarditis
Mixed Connective Tissue Disease
Pulmonary Hypertension
Early Diagnosis
Tomography
Hypereosinophilic Syndrome
Morbidity
Mortality
Systemic Scleroderma
Giant Cells
Sarcoidosis
Cardiac Catheterization
Cardiomyopathies
Systemic Lupus Erythematosus
Coronary Artery Disease
Anatomy
Coronary Vessels
Myocardium
Fibrosis

Keywords

  • Arterioles
  • Endocardium
  • Inflammatory disease
  • Myocarditis
  • Myocardium
  • Sarcoidosis

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Immunology and Allergy
  • Immunology

Cite this

Corda, M., Porcu, M., Atzeni, F., Gianturco, L., Sarzi-Puttini, P., & Turiel, M. (2017). New Cardiac Imaging Tools and Invasive Techniques in Systemic Autoimmune Diseases (Part II). In Handbook of Systemic Autoimmune Diseases (Vol. 14, pp. 209-226). (Handbook of Systemic Autoimmune Diseases; Vol. 14). Elsevier Ltd. https://doi.org/10.1016/B978-0-12-803997-7.00009-0

New Cardiac Imaging Tools and Invasive Techniques in Systemic Autoimmune Diseases (Part II). / Corda, M.; Porcu, M.; Atzeni, F.; Gianturco, L.; Sarzi-Puttini, P.; Turiel, M.

Handbook of Systemic Autoimmune Diseases. Vol. 14 Elsevier Ltd, 2017. p. 209-226 (Handbook of Systemic Autoimmune Diseases; Vol. 14).

Research output: Chapter in Book/Report/Conference proceedingChapter

Corda, M, Porcu, M, Atzeni, F, Gianturco, L, Sarzi-Puttini, P & Turiel, M 2017, New Cardiac Imaging Tools and Invasive Techniques in Systemic Autoimmune Diseases (Part II). in Handbook of Systemic Autoimmune Diseases. vol. 14, Handbook of Systemic Autoimmune Diseases, vol. 14, Elsevier Ltd, pp. 209-226. https://doi.org/10.1016/B978-0-12-803997-7.00009-0
Corda M, Porcu M, Atzeni F, Gianturco L, Sarzi-Puttini P, Turiel M. New Cardiac Imaging Tools and Invasive Techniques in Systemic Autoimmune Diseases (Part II). In Handbook of Systemic Autoimmune Diseases. Vol. 14. Elsevier Ltd. 2017. p. 209-226. (Handbook of Systemic Autoimmune Diseases). https://doi.org/10.1016/B978-0-12-803997-7.00009-0
Corda, M. ; Porcu, M. ; Atzeni, F. ; Gianturco, L. ; Sarzi-Puttini, P. ; Turiel, M. / New Cardiac Imaging Tools and Invasive Techniques in Systemic Autoimmune Diseases (Part II). Handbook of Systemic Autoimmune Diseases. Vol. 14 Elsevier Ltd, 2017. pp. 209-226 (Handbook of Systemic Autoimmune Diseases).
@inbook{d13166ba68024b7a8610ab01c6aceb71,
title = "New Cardiac Imaging Tools and Invasive Techniques in Systemic Autoimmune Diseases (Part II)",
abstract = "Systemic inflammatory diseases are associated with an increase in cardiovascular (CV) morbidity and mortality. CV involvement in systemic inflammatory diseases is highly heterogeneous, with manifestations affecting different heart structures. New instruments now allow an early diagnosis and prompt treatment. Over the last few years, Cardiac MRI has emerged as a noninvasive means of accurately and reproducibly assessing myocardial anatomy and function and has become the gold standard for measuring the ejection fraction, and left and right ventricular volumes. It can reveal myocardial lesions in patients with mixed connective tissue disease (CTD) and cardiac symptoms, including myocardial infarction, inflammation, and widespread subendocardial fibrosis and perfusion defects, which require further cardiac investigation and/or treatment. Computed tomography (CT) has evolved into such a potent means of diagnosis. It has become very important for cardiologists because it is widely available, easy to use, noninvasive, and highly sensitive in detecting coronary artery disease, and evaluating pericardial disease, pericardial fluid, and pericardial neoplasms. Radiation doses are a matter of concern and special measures need to be taken to avoid unnecessarily high doses when CT is used for coronary artery imaging. Pulmonary arterial hypertension (PAH) is one of the major complications of CTDs such as systemic sclerosis, systemic lupus erythematosus, and mixed CTD. Right heart catheterization is a fundamental means of confirming a diagnosis of PAH and assessing a risk that, when performed at dedicated centers, is associated with low morbidity and mortality rates. Myocarditis is an inflammatory disease of the myocardium caused by various infectious and noninfectious triggers. Systemic autoimmune diseases such as Churg–Strauss syndrome or hypereosinophilic syndrome (Loeffler's disease) can be associated with eosinophilic myocarditis. In the case of cardiac sarcoidosis and giant cell myocarditis, which are rare causes of inflammatory myocardial disease, early diagnosis and treatment significantly improve prognosis. The diagnostic gold standard is still an endomyocardial biopsy.",
keywords = "Arterioles, Endocardium, Inflammatory disease, Myocarditis, Myocardium, Sarcoidosis",
author = "M. Corda and M. Porcu and F. Atzeni and L. Gianturco and P. Sarzi-Puttini and M. Turiel",
year = "2017",
month = "1",
day = "1",
doi = "10.1016/B978-0-12-803997-7.00009-0",
language = "English",
volume = "14",
series = "Handbook of Systemic Autoimmune Diseases",
publisher = "Elsevier Ltd",
pages = "209--226",
booktitle = "Handbook of Systemic Autoimmune Diseases",

}

TY - CHAP

T1 - New Cardiac Imaging Tools and Invasive Techniques in Systemic Autoimmune Diseases (Part II)

AU - Corda, M.

AU - Porcu, M.

AU - Atzeni, F.

AU - Gianturco, L.

AU - Sarzi-Puttini, P.

AU - Turiel, M.

PY - 2017/1/1

Y1 - 2017/1/1

N2 - Systemic inflammatory diseases are associated with an increase in cardiovascular (CV) morbidity and mortality. CV involvement in systemic inflammatory diseases is highly heterogeneous, with manifestations affecting different heart structures. New instruments now allow an early diagnosis and prompt treatment. Over the last few years, Cardiac MRI has emerged as a noninvasive means of accurately and reproducibly assessing myocardial anatomy and function and has become the gold standard for measuring the ejection fraction, and left and right ventricular volumes. It can reveal myocardial lesions in patients with mixed connective tissue disease (CTD) and cardiac symptoms, including myocardial infarction, inflammation, and widespread subendocardial fibrosis and perfusion defects, which require further cardiac investigation and/or treatment. Computed tomography (CT) has evolved into such a potent means of diagnosis. It has become very important for cardiologists because it is widely available, easy to use, noninvasive, and highly sensitive in detecting coronary artery disease, and evaluating pericardial disease, pericardial fluid, and pericardial neoplasms. Radiation doses are a matter of concern and special measures need to be taken to avoid unnecessarily high doses when CT is used for coronary artery imaging. Pulmonary arterial hypertension (PAH) is one of the major complications of CTDs such as systemic sclerosis, systemic lupus erythematosus, and mixed CTD. Right heart catheterization is a fundamental means of confirming a diagnosis of PAH and assessing a risk that, when performed at dedicated centers, is associated with low morbidity and mortality rates. Myocarditis is an inflammatory disease of the myocardium caused by various infectious and noninfectious triggers. Systemic autoimmune diseases such as Churg–Strauss syndrome or hypereosinophilic syndrome (Loeffler's disease) can be associated with eosinophilic myocarditis. In the case of cardiac sarcoidosis and giant cell myocarditis, which are rare causes of inflammatory myocardial disease, early diagnosis and treatment significantly improve prognosis. The diagnostic gold standard is still an endomyocardial biopsy.

AB - Systemic inflammatory diseases are associated with an increase in cardiovascular (CV) morbidity and mortality. CV involvement in systemic inflammatory diseases is highly heterogeneous, with manifestations affecting different heart structures. New instruments now allow an early diagnosis and prompt treatment. Over the last few years, Cardiac MRI has emerged as a noninvasive means of accurately and reproducibly assessing myocardial anatomy and function and has become the gold standard for measuring the ejection fraction, and left and right ventricular volumes. It can reveal myocardial lesions in patients with mixed connective tissue disease (CTD) and cardiac symptoms, including myocardial infarction, inflammation, and widespread subendocardial fibrosis and perfusion defects, which require further cardiac investigation and/or treatment. Computed tomography (CT) has evolved into such a potent means of diagnosis. It has become very important for cardiologists because it is widely available, easy to use, noninvasive, and highly sensitive in detecting coronary artery disease, and evaluating pericardial disease, pericardial fluid, and pericardial neoplasms. Radiation doses are a matter of concern and special measures need to be taken to avoid unnecessarily high doses when CT is used for coronary artery imaging. Pulmonary arterial hypertension (PAH) is one of the major complications of CTDs such as systemic sclerosis, systemic lupus erythematosus, and mixed CTD. Right heart catheterization is a fundamental means of confirming a diagnosis of PAH and assessing a risk that, when performed at dedicated centers, is associated with low morbidity and mortality rates. Myocarditis is an inflammatory disease of the myocardium caused by various infectious and noninfectious triggers. Systemic autoimmune diseases such as Churg–Strauss syndrome or hypereosinophilic syndrome (Loeffler's disease) can be associated with eosinophilic myocarditis. In the case of cardiac sarcoidosis and giant cell myocarditis, which are rare causes of inflammatory myocardial disease, early diagnosis and treatment significantly improve prognosis. The diagnostic gold standard is still an endomyocardial biopsy.

KW - Arterioles

KW - Endocardium

KW - Inflammatory disease

KW - Myocarditis

KW - Myocardium

KW - Sarcoidosis

UR - http://www.scopus.com/inward/record.url?scp=85020694408&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85020694408&partnerID=8YFLogxK

U2 - 10.1016/B978-0-12-803997-7.00009-0

DO - 10.1016/B978-0-12-803997-7.00009-0

M3 - Chapter

AN - SCOPUS:85020694408

VL - 14

T3 - Handbook of Systemic Autoimmune Diseases

SP - 209

EP - 226

BT - Handbook of Systemic Autoimmune Diseases

PB - Elsevier Ltd

ER -