New Cardiopulmonary Resuscitation Guidelines 2005: Importance of Uninterrupted Chest Compression

Giuseppe Ristagno, Antonino Gullo, Wanchun Tang, Max Harry Weil

Research output: Contribution to journalArticlepeer-review


Interruptions of chest compression are detrimental because they increase the severity of ischemic injury both to the heart and to other vital organs including the brain. The evidence supports quality controlled chest compression as the initial intervention after sudden death before attempted defibrillation, if the duration of cardiac arrest is more than 5 minutes. Chest compressions of themselves provide forward blood flow with restoration of myocardial and cerebral blood flows. The resulting restorations of coronary and myocardial blood flow increase the success of initial resuscitation, and secure better postresuscitation myocardial function, neurologic outcomes, and survival. The new guidelines mandate lesser interruptions for ventilation, before and following electrical shocks, and single rather than multiple electrical shocks before resuming chest compression. The new guidelines refocus on uninterrupted chest compression after cardiac arrest of nonasphyxial cause and modifications in practices that reduce the need for interruptions.

Original languageEnglish
Pages (from-to)531-538
Number of pages8
JournalCritical Care Clinics
Issue number3
Publication statusPublished - Jul 2006

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine


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