New cell-based technologies in bone and cartilage tissue engineering. I. Bone reconstruction.

M. Marcacci, E. Kon, S. Zaffagnini, A. Vascellari, M. P. Neri, F. Iacono

Research output: Contribution to journalArticle

Abstract

A tissue engineering, cell-based therapeutic approach could be essential for extensive bone or cartilage reconstruction. This article is divided in two chapters and describes new cell-based surgical techniques for cartilage and bone reconstruction. In the first part on bone reconstruction, marrow-derived osteogenic progenitor cells combined with hydroxyapatite were utilized. The validity of this model has been shown for the repair of critical size bone defects in large size animal models. We used this cell-based therapeutic approach to treat 3 patients with large bone defects, achieving bone reconstruction.

Original languageEnglish
Pages (from-to)33-42
Number of pages10
JournalLa Chirurgia degli organi di movimento
Volume88
Issue number1
Publication statusPublished - 2003

Fingerprint Dive into the research topics of 'New cell-based technologies in bone and cartilage tissue engineering. I. Bone reconstruction.'. Together they form a unique fingerprint.

  • Cite this