New Diagnostic Possibilities for Neonatal Sepsis

Chryssoula Tzialla, Paolo Manzoni, Cristian Achille, Lina Bollani, Mauro Stronati, Alessandro Borghesi

Research output: Contribution to journalArticlepeer-review


Progress in neonatal care has decrease morbidity and mortality due to neonatal sepsis (NS). Although diagnosis of sepsis continues to rely on blood culture, this method is too slow and limited by false-negative results. There are numerous sepsis biomarkers that have been evaluated for the early diagnosis of NS, but, to date, there is no single ideal biomarker, though novel biomarkers are becoming more sophisticated and specific in their clinical applications. This review provides an overview of the current diagnostic approaches available or under development for diagnosing NS.

Original languageEnglish
Pages (from-to)575-577
Number of pages3
JournalAmerican Journal of Perinatology
Issue number6
Publication statusPublished - May 1 2018
Externally publishedYes


  • biomarkers
  • diagnosis
  • neonate
  • sepsis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynaecology


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