Abstract
Despite the many outstanding favorable results achieved in the treatment of hypertension, several unmet goals of antihypertensive therapy remain, such as better blood pressure control, greater protection against the organ damage associated with hypertension, better tolerability, and ultimately a more effective prevention of cardiovascular disease. These unmet goals are the reasons why new antihypertensive drugs are synthesized and tested in the clinical practice. This paper briefly mentions the goals of new antihypertensive agents and examines the main pharmacological and clinical features of new classes of antihypertensive drugs, such as angiotensin II receptor blockers, central agents, vasopeptidase inhibitors, and endothelin antagonists. The results of experimental and clinical studies with these new drugs are reviewed, emphasizing some advantages and potential disadvantages of these drugs compared with traditional antihypertensive drugs.
| Original language | English |
|---|---|
| Pages (from-to) | 375-380 |
| Number of pages | 6 |
| Journal | Current Opinion in Cardiology |
| Volume | 14 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 1999 |
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ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
New drugs for the treatment of hypertension. / Mancia, Giuseppe; Stella, Maria Luisa; Grassi, Guido.
In: Current Opinion in Cardiology, Vol. 14, No. 5, 1999, p. 375-380.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - New drugs for the treatment of hypertension
AU - Mancia, Giuseppe
AU - Stella, Maria Luisa
AU - Grassi, Guido
PY - 1999
Y1 - 1999
N2 - Despite the many outstanding favorable results achieved in the treatment of hypertension, several unmet goals of antihypertensive therapy remain, such as better blood pressure control, greater protection against the organ damage associated with hypertension, better tolerability, and ultimately a more effective prevention of cardiovascular disease. These unmet goals are the reasons why new antihypertensive drugs are synthesized and tested in the clinical practice. This paper briefly mentions the goals of new antihypertensive agents and examines the main pharmacological and clinical features of new classes of antihypertensive drugs, such as angiotensin II receptor blockers, central agents, vasopeptidase inhibitors, and endothelin antagonists. The results of experimental and clinical studies with these new drugs are reviewed, emphasizing some advantages and potential disadvantages of these drugs compared with traditional antihypertensive drugs.
AB - Despite the many outstanding favorable results achieved in the treatment of hypertension, several unmet goals of antihypertensive therapy remain, such as better blood pressure control, greater protection against the organ damage associated with hypertension, better tolerability, and ultimately a more effective prevention of cardiovascular disease. These unmet goals are the reasons why new antihypertensive drugs are synthesized and tested in the clinical practice. This paper briefly mentions the goals of new antihypertensive agents and examines the main pharmacological and clinical features of new classes of antihypertensive drugs, such as angiotensin II receptor blockers, central agents, vasopeptidase inhibitors, and endothelin antagonists. The results of experimental and clinical studies with these new drugs are reviewed, emphasizing some advantages and potential disadvantages of these drugs compared with traditional antihypertensive drugs.
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UR - http://www.scopus.com/inward/citedby.url?scp=0032822422&partnerID=8YFLogxK
U2 - 10.1097/00001573-199909000-00004
DO - 10.1097/00001573-199909000-00004
M3 - Article
VL - 14
SP - 375
EP - 380
JO - Current Opinion in Cardiology
JF - Current Opinion in Cardiology
SN - 0268-4705
IS - 5
ER -