New drugs in development for the treatment of endometriosis

Luigi Fedele, Edgardo Somigliana, Giada Frontino, Laura Benaglia, Paola Vigano

Research output: Contribution to journalArticlepeer-review


Endometriosis is a common and enigmatic disease causing pelvic pain and infertility. Current treatment is mainly based on the use of surgery and ovarian suppressive agents. There is in particular the need for new therapeutic options able to allow a normal menstrual cycle to occur and also consent pregnancy. In the present review, we aimed to give a concise and practical overview in order to allow the clinician to clearly understand the level of development of these drugs. We have presented only treatments supported by in vivo researches with a special attention to studies in humans. Results show appealing new possibilities are emerging from agents counteracting the endometriosis-associated inflammation. Recent data also suggests that there is still the opportunity to refine the use of already available agents.

Original languageEnglish
Pages (from-to)1187-1202
Number of pages16
JournalExpert Opinion on Investigational Drugs
Issue number8
Publication statusPublished - Aug 2008


  • Endometriosis
  • Inflammation
  • Treatment

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Pharmacology

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