TY - JOUR
T1 - New evidence for the cerebellar involvement in personality traits
AU - Picerni, Eleonora
AU - Petrosini, Laura
AU - Piras, Fabrizio
AU - Laricchiuta, Daniela
AU - Cutuli, Debora
AU - Chiapponi, Chiara
AU - Fagioli, Sabrina
AU - Girardi, Paolo
AU - Caltagirone, Carlo
AU - Spalletta, Gianfranco
PY - 2013
Y1 - 2013
N2 - Following the recognition of its role in sensory-motor coordination and learning, the cerebellum has been involved in cognitive, emotional, and even personality domains. This study investigated the relationships between cerebellar macro- and micro-structural variations and temperamental traits measured by Temperament and Character Inventory (TCI). High resolution T1-weighted, and Diffusion Tensor Images of 100 healthy subjects aged 18-59 years were acquired by 3 Tesla Magnetic Resonance scanner. In multiple regression analyses, cerebellar Gray Matter (GM) or White Matter (WM) volumes, GM Mean Diffusivity (MD), and WM Fractional Anisotropy (FA) were used as dependent variables, TCI scores as regressors, gender, age, and education years as covariates. Novelty Seeking scores were associated positively with the cerebellar GM volumes and FA, and negatively with MD. No significant association between Harm Avoidance, Reward Dependence or Persistence scores and cerebellar structural measures was found. The present data put toward a cerebellar involvement in the management of novelty.
AB - Following the recognition of its role in sensory-motor coordination and learning, the cerebellum has been involved in cognitive, emotional, and even personality domains. This study investigated the relationships between cerebellar macro- and micro-structural variations and temperamental traits measured by Temperament and Character Inventory (TCI). High resolution T1-weighted, and Diffusion Tensor Images of 100 healthy subjects aged 18-59 years were acquired by 3 Tesla Magnetic Resonance scanner. In multiple regression analyses, cerebellar Gray Matter (GM) or White Matter (WM) volumes, GM Mean Diffusivity (MD), and WM Fractional Anisotropy (FA) were used as dependent variables, TCI scores as regressors, gender, age, and education years as covariates. Novelty Seeking scores were associated positively with the cerebellar GM volumes and FA, and negatively with MD. No significant association between Harm Avoidance, Reward Dependence or Persistence scores and cerebellar structural measures was found. The present data put toward a cerebellar involvement in the management of novelty.
KW - Fractional anisotropy
KW - Individual differences
KW - Mean diffusivity
KW - Novelty seeking
KW - Temperamental traits
KW - Voxel-based morphometry
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U2 - 10.3389/fnbeh.2013.00133
DO - 10.3389/fnbeh.2013.00133
M3 - Article
C2 - 24106465
AN - SCOPUS:84886301142
JO - Frontiers in Behavioral Neuroscience
JF - Frontiers in Behavioral Neuroscience
SN - 1662-5153
IS - OCT
M1 - 133
ER -