New evidence for the cerebellar involvement in personality traits

Eleonora Picerni, Laura Petrosini, Fabrizio Piras, Daniela Laricchiuta, Debora Cutuli, Chiara Chiapponi, Sabrina Fagioli, Paolo Girardi, Carlo Caltagirone, Gianfranco Spalletta

Research output: Contribution to journalArticlepeer-review

Abstract

Following the recognition of its role in sensory-motor coordination and learning, the cerebellum has been involved in cognitive, emotional, and even personality domains. This study investigated the relationships between cerebellar macro- and micro-structural variations and temperamental traits measured by Temperament and Character Inventory (TCI). High resolution T1-weighted, and Diffusion Tensor Images of 100 healthy subjects aged 18-59 years were acquired by 3 Tesla Magnetic Resonance scanner. In multiple regression analyses, cerebellar Gray Matter (GM) or White Matter (WM) volumes, GM Mean Diffusivity (MD), and WM Fractional Anisotropy (FA) were used as dependent variables, TCI scores as regressors, gender, age, and education years as covariates. Novelty Seeking scores were associated positively with the cerebellar GM volumes and FA, and negatively with MD. No significant association between Harm Avoidance, Reward Dependence or Persistence scores and cerebellar structural measures was found. The present data put toward a cerebellar involvement in the management of novelty.

Original languageEnglish
Article number133
JournalFrontiers in Behavioral Neuroscience
Issue numberOCT
DOIs
Publication statusPublished - 2013

Keywords

  • Fractional anisotropy
  • Individual differences
  • Mean diffusivity
  • Novelty seeking
  • Temperamental traits
  • Voxel-based morphometry

ASJC Scopus subject areas

  • Behavioral Neuroscience
  • Cognitive Neuroscience
  • Neuropsychology and Physiological Psychology

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