New insights on the origin of the VLF cardiorespiratory rhythm in chronic heart failure patients

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this study we investigated in a group of 14 chronic heart failure (CHF) patients (pts) showing a periodic breathing (PB) pattern 1) the phase relationship between ventilation and arterial O2 saturation to verify the respiratory control instability hypothesis of PB 2) the relationship between these signals and heart period (HP) variability. A clear very low frequency (VLF) oscillation around 0.02 Hz, associated with PB, was observed in the instantaneous lung volume (ILV), instantaneous minute ventilation (IMV), O2 saturation at the ear (SpO2) and HP signals. Coherence between signals was on average > =0.8, thus confirming that during PB a more general cardio-respiratory rhythm takes place. The median phase lag between IMV and SpO2 was -206° (IMV leads); between ILV and HP was -202° (ILV leads). SpO2 and HP were almost synchronous. Our findings are consistent with and clearly support the instability hypothesis for PB. As concerns the link between respiratory and HP oscillations our results point out that, besides central coupling and lung stretch receptors feedback, an important role in the linkage between respiratory and cardiovascular regulation might be played by arterial chemoreceptors.

Original languageEnglish
Title of host publicationComputers in Cardiology
PublisherIEEE
Pages205-208
Number of pages4
Publication statusPublished - 1995
EventProceedings of the 1995 Conference on Computers in Cardiology - Vienna, Austria
Duration: Sep 10 1995Sep 13 1995

Other

OtherProceedings of the 1995 Conference on Computers in Cardiology
CityVienna, Austria
Period9/10/959/13/95

ASJC Scopus subject areas

  • Software
  • Cardiology and Cardiovascular Medicine

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