NUOVE METODICHE PER IL DOSAGGIO DI IGE SPECIFICHE IN RAPPORTO AI SINTOMI CLINICI NELLE ALLERGOPATIE RESPIRATORIE

Translated title of the contribution: New methods for specific IgE determination and their relation to clinical symptoms in respiratory allergopathies

I. J. Ansotegui, E. Scala, E. Fanales-Belasio, R. Paganelli

Research output: Contribution to journalArticle

Abstract

The aim of this study is to evaluate the diagnostic accuracy of the ENEA System in relation with skin prick test as diagnostic tool in inhalant allergy. We studied 130 subjects, 67 atopic and 63 non-atopic. The atopic patients were selected on the basis of the following criteria: 1) familiar and/or personal history of atopy; 2) positive skin prick test (spt) to at least one of the following allergens: Dermatophagoides pteronyssimus, Parietaria judaica and Lolium perenne; 3) presence of clinical symptoms like seasonal rhinitis or rhinoconjuntivitis and/or asthma. Our data show that the most important characteristic of the ENEA System was its very high specificity (96.02%) with a good sensitivity, detecting more than 91% of all positivities by spt to inhalant allergens. The efficiency resulted higher of 93% for each allergen tested. Furthermore, the ENEA System resulted very accurate in the intra-assay results.

Translated title of the contributionNew methods for specific IgE determination and their relation to clinical symptoms in respiratory allergopathies
Original languageItalian
Pages (from-to)361-365
Number of pages5
JournalGiornale Italiano di Chimica Clinica
Volume18
Issue number5-6
Publication statusPublished - 1993

ASJC Scopus subject areas

  • Clinical Biochemistry

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