New microsurgical technique using sciatic nerve repair in the rat using venous graft: Functional and morphological results

G. Zetti, G. Fioretta, S. Gatti, P. Premoselli, C. Cappa, P. Marchettini, M. Sessa, M. Comola, G. Ferla

Research output: Contribution to journalArticlepeer-review

Abstract

Morphological and functional evaluation of nerve regeneration, using an autogenous vein graft placed between the two extremities of a transected peripheral nerve has been carried out employing an original microsurgical technique. In 25 Wistar rats, weighing 200 g, a segment of the right sciatic nerve was resected, leaving a gap of about 1 cm. between the stumps, later bridged with an autogenous femoral vein graft. A neurophysiological evaluation of nerve regeneration was done studying the distal motor latency of the right sciatic nerve while the morphological evaluation was done, carrying out both histological sections of the nerve and biopsies of the tibialis anterior muscle. Nerve conduction after the twelfth week from the operation has shown restoration trough the vein-grafted right sciatic nerves in all the animals and pathognomonic features of reinnervation muscle process were demonstrated in the operated side.

Original languageEnglish
Pages (from-to)149-158
Number of pages10
JournalSurgical Research Communications
Volume6
Issue number2
Publication statusPublished - 1989

ASJC Scopus subject areas

  • Surgery

Fingerprint Dive into the research topics of 'New microsurgical technique using sciatic nerve repair in the rat using venous graft: Functional and morphological results'. Together they form a unique fingerprint.

Cite this