Morphological and functional evaluation of nerve regeneration, using an autogenous vein graft placed between the two extremities of a transected peripheral nerve has been carried out employing an original microsurgical technique. In 25 Wistar rats, weighing 200 g, a segment of the right sciatic nerve was resected, leaving a gap of about 1 cm. between the stumps, later bridged with an autogenous femoral vein graft. A neurophysiological evaluation of nerve regeneration was done studying the distal motor latency of the right sciatic nerve while the morphological evaluation was done, carrying out both histological sections of the nerve and biopsies of the tibialis anterior muscle. Nerve conduction after the twelfth week from the operation has shown restoration trough the vein-grafted right sciatic nerves in all the animals and pathognomonic features of reinnervation muscle process were demonstrated in the operated side.
|Number of pages||10|
|Journal||Surgical Research Communications|
|Publication status||Published - 1989|
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