New morphologic variants of the hand motor cortex as seen with MR imaging in a large study population

Massimo Caulo, C. Briganti, P. A. Mattei, B. Perfetti, A. Ferretti, G. L. Romani, A. Tartaro, C. Colosimo

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

BACKGROUND AND PURPOSE: The hand motor cortex (HMC) has been classically described as having an omega or epsilon shape in axial-plane images obtained with CT and MR imaging. The aim of this study was to use MR imaging and Talairach normalization in a large sample population that was homogeneous for age and handedness to evaluate in a sex model a new classification with 5 morphologic variants of the HMC in the axial plane (omega, medially asymmetric epsilon, epsilon, laterally asymmetric epsilon, and null). MATERIALS AND METHODS: Structural brain MR images were obtained from 257 right-handed healthy subjects (143 men and 114 women; mean age, 23.1 ± 1.1 years) via a Talairach space transformed 3D magnetization-prepared rapid acquisition of gradient echo sequence. The frequencies of the different HMC variants were reported for hemisphere and sex. RESULTS: The new variants of the HMC (medially asymmetric epsilon, laterally asymmetric epsilon, and null) were observed in 2.9%, 7.0%, and 1.8% of the hemispheres, respectively. Statistically significant sex differences were observed: The epsilon variant was twice as frequent in men, and an interhemispheric concordance for morphologic variants was observed only for women. CONCLUSION: The large study population permitted the description of a new morphologic classification that included 3 new variants of the HMC. This new morphologic classification should facilitate the identification of the precentral gyrus in subsequent studies and in everyday practice.

Original languageEnglish
Pages (from-to)1480-1485
Number of pages6
JournalAmerican Journal of Neuroradiology
Volume28
Issue number8
DOIs
Publication statusPublished - Sep 2007

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Motor Cortex
Hand
Population
Functional Laterality
Frontal Lobe
Sex Characteristics
Healthy Volunteers
Brain

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Caulo, M., Briganti, C., Mattei, P. A., Perfetti, B., Ferretti, A., Romani, G. L., ... Colosimo, C. (2007). New morphologic variants of the hand motor cortex as seen with MR imaging in a large study population. American Journal of Neuroradiology, 28(8), 1480-1485. https://doi.org/10.3174/ajnr.A0597

New morphologic variants of the hand motor cortex as seen with MR imaging in a large study population. / Caulo, Massimo; Briganti, C.; Mattei, P. A.; Perfetti, B.; Ferretti, A.; Romani, G. L.; Tartaro, A.; Colosimo, C.

In: American Journal of Neuroradiology, Vol. 28, No. 8, 09.2007, p. 1480-1485.

Research output: Contribution to journalArticle

Caulo, M, Briganti, C, Mattei, PA, Perfetti, B, Ferretti, A, Romani, GL, Tartaro, A & Colosimo, C 2007, 'New morphologic variants of the hand motor cortex as seen with MR imaging in a large study population', American Journal of Neuroradiology, vol. 28, no. 8, pp. 1480-1485. https://doi.org/10.3174/ajnr.A0597
Caulo, Massimo ; Briganti, C. ; Mattei, P. A. ; Perfetti, B. ; Ferretti, A. ; Romani, G. L. ; Tartaro, A. ; Colosimo, C. / New morphologic variants of the hand motor cortex as seen with MR imaging in a large study population. In: American Journal of Neuroradiology. 2007 ; Vol. 28, No. 8. pp. 1480-1485.
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