TY - JOUR
T1 - New-onset left atrial enlargement in a general population
AU - Bombelli, Michele
AU - Cuspidi, Cesare
AU - Facchetti, Rita
AU - Sala, Carla
AU - Tadic, Marijana
AU - Brambilla, Gianmaria
AU - Re, Annalisa
AU - Villa, Paolo
AU - Grassi, Guido
AU - Mancia, Giuseppe
PY - 2016/7/1
Y1 - 2016/7/1
N2 - AIM:: Increased left atrium diameter (LAD) is associated with elevated risk of cardiovascular morbidity and mortality. We evaluated new-onset left atrium enlargement (LAE) and their correlates over a 10-year period in participants of the general population enrolled in the Pressioni Monitorate e Loro Associazioni study. METHODS:: The study included 1045 participants with normal LAD at baseline evaluation having a readable echocardiogram at the end of follow-up. Cut-points for abnormal LAD were derived from reference values recommended by American Society of Echocardiography. RESULTS:: Over a 10-year period, 123 participants (11.8%) progressed to LAE. The incidence of new-onset LAE increased significantly from the lowest to the highest tertile of baseline office, home and 24-h blood pressure (BP); BMI; fasting blood glucose and left ventricular mass index (LVMI). In multivariate analysis, baseline LAD [odds ratio (OR) 3.18, confidence interval (CI) 2.26–4.47, P?
AB - AIM:: Increased left atrium diameter (LAD) is associated with elevated risk of cardiovascular morbidity and mortality. We evaluated new-onset left atrium enlargement (LAE) and their correlates over a 10-year period in participants of the general population enrolled in the Pressioni Monitorate e Loro Associazioni study. METHODS:: The study included 1045 participants with normal LAD at baseline evaluation having a readable echocardiogram at the end of follow-up. Cut-points for abnormal LAD were derived from reference values recommended by American Society of Echocardiography. RESULTS:: Over a 10-year period, 123 participants (11.8%) progressed to LAE. The incidence of new-onset LAE increased significantly from the lowest to the highest tertile of baseline office, home and 24-h blood pressure (BP); BMI; fasting blood glucose and left ventricular mass index (LVMI). In multivariate analysis, baseline LAD [odds ratio (OR) 3.18, confidence interval (CI) 2.26–4.47, P?
UR - http://www.scopus.com/inward/record.url?scp=84977151335&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84977151335&partnerID=8YFLogxK
U2 - 10.1097/HJH.0000000000001022
DO - 10.1097/HJH.0000000000001022
M3 - Article
AN - SCOPUS:84977151335
JO - Journal of Hypertension
JF - Journal of Hypertension
SN - 0263-6352
ER -