New parameters for identifying subclinical atherosclerosis in patients with primary Sjögren's syndrome: A pilot study

Fabiola Atzeni, Piercarlo Sarzi-puttini, Maria Chiara Signorello, Luigi Gianturco, Daniele Stella, Laura Boccassini, Cristian Ricci, Bruno Dino Bodini, Alberto Batticciotto, Vito De Gennaro-Colonna, Lorenzo Drago, Maurizio Turiel

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: We investigated sub-clinical cardiovascular involvement in primary Sjögren's syndrome (pSS) patients by means of ADMA, coronary flow reserve (CFR), intima media thickness (cIMT), pulse wave velocity (PWV) and myocardial deformation. Methods: The study involved 22 outpatients with pSS (6 males, 16 females; mean age 60.14±7.81 years) and no documentable cardiovascular disease, and 22 age- and gender-matched controls. Dipyridamole transthoracic stress echocardiography was used to evaluate wall motion and CFR. A CFR value of

Original languageEnglish
Pages (from-to)361-368
Number of pages8
JournalClinical and Experimental Rheumatology
Volume32
Issue number3
Publication statusPublished - 2014

Keywords

  • Arterial stiffness
  • Atherosclerosis
  • Connective tissue diseases
  • Sjögren's syndrome
  • Speckle tracking echocardiography

ASJC Scopus subject areas

  • Rheumatology
  • Immunology
  • Immunology and Allergy

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