Abstract
We report that the allele distribution for RFLP's flanking the CF gene differs between patients with and without pancreatic insufficiency. The present study confirms this difference. In both classes the linkage disequilibrium (LD) is highest with the RFLP revealed by probe E9. The haplotype distribution identified by these RFLP's can be used for indirect carrier detection.
| Original language | English |
|---|---|
| Pages (from-to) | 102-104 |
| Number of pages | 3 |
| Journal | Acta Universitatis Carolinae Medica |
| Volume | 36 |
| Issue number | 1-4 |
| Publication status | Published - 1990 |
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- Medicine(all)
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New restriction fragment length polymorphism (probe E9) reveals the highest linkage disequilibrium in Italian CF patients. / Devoto, M.; De Benedetti, L.; Ronchetto, P.; Romano, L.; Romeo, G.; Tsui, L. C.; Dean, M.; Collins, F.; Seia, M.; Piceni Sereni, L.
In: Acta Universitatis Carolinae Medica, Vol. 36, No. 1-4, 1990, p. 102-104.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - New restriction fragment length polymorphism (probe E9) reveals the highest linkage disequilibrium in Italian CF patients.
AU - Devoto, M.
AU - De Benedetti, L.
AU - Ronchetto, P.
AU - Romano, L.
AU - Romeo, G.
AU - Tsui, L. C.
AU - Dean, M.
AU - Collins, F.
AU - Seia, M.
AU - Piceni Sereni, L.
PY - 1990
Y1 - 1990
N2 - We report that the allele distribution for RFLP's flanking the CF gene differs between patients with and without pancreatic insufficiency. The present study confirms this difference. In both classes the linkage disequilibrium (LD) is highest with the RFLP revealed by probe E9. The haplotype distribution identified by these RFLP's can be used for indirect carrier detection.
AB - We report that the allele distribution for RFLP's flanking the CF gene differs between patients with and without pancreatic insufficiency. The present study confirms this difference. In both classes the linkage disequilibrium (LD) is highest with the RFLP revealed by probe E9. The haplotype distribution identified by these RFLP's can be used for indirect carrier detection.
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UR - http://www.scopus.com/inward/citedby.url?scp=0025584597&partnerID=8YFLogxK
M3 - Article
VL - 36
SP - 102
EP - 104
JO - Acta Universitatis Carolinae Medica
JF - Acta Universitatis Carolinae Medica
SN - 0001-7116
IS - 1-4
ER -