New sepsis biomarkers

Dolores Limongi, Cartesio D'Agostini, Marco Ciotti

Research output: Contribution to journalArticle

Abstract

Sepsis remains a leading cause of death in the intensive care units and in all age groups worldwide. Early recognition and diagnosis are key to achieving improved outcomes. Therefore, novel biomarkers that might better inform clinicians treating such patients are surely needed. The main attributes of successful biomarkers would be high sensitivity, specificity, possibility of bedside monitoring and financial accessibility. A panel of sepsis biomarkers along with currently used laboratory tests will facilitate earlier diagnosis, timely treatment and improved outcome may be more effective than single biomarkers. In this review, we summarize the most recent advances on sepsis biomarkers evaluated in clinical and experimental studies.

Original languageEnglish
JournalAsian Pacific Journal of Tropical Biomedicine
DOIs
Publication statusAccepted/In press - Dec 19 2015

Keywords

  • Biomarker
  • Hepcidin
  • Interleukin-27
  • Macrophage migration inhibitory factor
  • Plasma chitotriosidase
  • Presepsin
  • Sepsis

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology (miscellaneous)

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