New strategies for the treatment of migraine attacks

Sergio Genco, Domenico D'Amico, Franca Moschiano, Maria Pia Prudenzano, Paola Mosconi, Elena Floriani, Ferdinando Schieroni, Gennaro Bussone

Research output: Contribution to journalArticle

Abstract

There is no consensus on which treatment strategy should be used in the acute therapy of migraine. A stratified care approach based on patient's disability assessed by a valid instrument (the MIDAS questionnaire) has been proposed. An international controlled study, the DISC trial, showed that stratified care provided better clinical outcomes than step care across attacks or within attacks. An Italian study invited migraine patients with moderate-severe disability to treat 9 attacks according to one of two strategies: stratified care (i.e. triptans from the outset) or step care across attacks (i.e. with drug escalation from non-specific drugs to triptans, if the response was not satisfactory). This study should provide data useful for assessing the optimal treatment strategy in migraine.

Original languageEnglish
JournalJournal of Headache and Pain
Volume2
Issue numberSUPPL. 1
DOIs
Publication statusPublished - 2001

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Migraine Disorders
Tryptamines
Pharmaceutical Preparations
Therapeutics

Keywords

  • Acute treatment
  • Migraine
  • Step care
  • Stratified care
  • Triptans

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine
  • Neuroscience(all)

Cite this

Genco, S., D'Amico, D., Moschiano, F., Prudenzano, M. P., Mosconi, P., Floriani, E., ... Bussone, G. (2001). New strategies for the treatment of migraine attacks. Journal of Headache and Pain, 2(SUPPL. 1). https://doi.org/10.1007/s101940170022

New strategies for the treatment of migraine attacks. / Genco, Sergio; D'Amico, Domenico; Moschiano, Franca; Prudenzano, Maria Pia; Mosconi, Paola; Floriani, Elena; Schieroni, Ferdinando; Bussone, Gennaro.

In: Journal of Headache and Pain, Vol. 2, No. SUPPL. 1, 2001.

Research output: Contribution to journalArticle

Genco, S, D'Amico, D, Moschiano, F, Prudenzano, MP, Mosconi, P, Floriani, E, Schieroni, F & Bussone, G 2001, 'New strategies for the treatment of migraine attacks', Journal of Headache and Pain, vol. 2, no. SUPPL. 1. https://doi.org/10.1007/s101940170022
Genco, Sergio ; D'Amico, Domenico ; Moschiano, Franca ; Prudenzano, Maria Pia ; Mosconi, Paola ; Floriani, Elena ; Schieroni, Ferdinando ; Bussone, Gennaro. / New strategies for the treatment of migraine attacks. In: Journal of Headache and Pain. 2001 ; Vol. 2, No. SUPPL. 1.
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