TY - JOUR
T1 - New surfaces with hydrophilic/hydrophobic characteristics in relations to (no)bioadhesion
AU - Legeay, G.
AU - Poncin-Epaillard, F.
AU - Arciola, C. R.
PY - 2006/4
Y1 - 2006/4
N2 - The possibility of biosurfaces with high or low adhesiveness for protein, bacteria or eukaryotic cells is discussed. At the interface su rface object/biological milieu, biocompatibility, (no) bioadhesion and (no) biocontamination are shown to be correlated with physico-chemical surface characteristics. First consequence is the (no) possibility of biofilm formation. Substrates with low surface energy could interact only with hydrophobic biomolecules. On substrates with high surface energy, a water monolayer spontaneously formed. Modification of a surface by plasma techniques is a way for engineering biomaterials. Plasma techniques are dry processes and more suitable for biomedical applications. In the field of biomaterial medical devices, in hygienic prevention of nosocomial diseases, in food packaging, the use of substrates with a very hydrophilic character may help to prevent the proliferation of cells and bacteria. Such a technique is so efficient that antibiotic molecules are not necessary. Therefore, surface engineering is a tool for modifying and adapting materials to specific biological applications.
AB - The possibility of biosurfaces with high or low adhesiveness for protein, bacteria or eukaryotic cells is discussed. At the interface su rface object/biological milieu, biocompatibility, (no) bioadhesion and (no) biocontamination are shown to be correlated with physico-chemical surface characteristics. First consequence is the (no) possibility of biofilm formation. Substrates with low surface energy could interact only with hydrophobic biomolecules. On substrates with high surface energy, a water monolayer spontaneously formed. Modification of a surface by plasma techniques is a way for engineering biomaterials. Plasma techniques are dry processes and more suitable for biomedical applications. In the field of biomaterial medical devices, in hygienic prevention of nosocomial diseases, in food packaging, the use of substrates with a very hydrophilic character may help to prevent the proliferation of cells and bacteria. Such a technique is so efficient that antibiotic molecules are not necessary. Therefore, surface engineering is a tool for modifying and adapting materials to specific biological applications.
KW - Bioadhesion
KW - Hydrophilic
KW - Hydrophobic
KW - Surfaces
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M3 - Article
C2 - 16705615
AN - SCOPUS:33745233340
VL - 29
SP - 453
EP - 461
JO - International Journal of Artificial Organs
JF - International Journal of Artificial Organs
SN - 0391-3988
IS - 4
ER -