Abstract
In painful bladder syndrome of phlogistic outcome, diagnostic assessment is able to distinguish between bacterial and non bacterial cystitis and endoscopy to evaluate the presence of leucoplasic trigonitis. In absence of infection or leucoplasia we propose the following management: bladder instillation (twice a week for a month) with oxybutynin 20 mg in 20 cc of saline solution. Desmopressine (0,2 cc by nasal drops) three hours before irrigation. On 12 patients all were cured at one year follow up even if 40% needed a second treatment. No side effects were described. Urine flow prevents effectiveness of direct administration of drugs in bladder. Oxybutynin is otherwise not long tolerated for well known side effects. The association with DDAVP (Desmopressine) makes the treatment reliable.
| Original language | English |
|---|---|
| Pages (from-to) | 53-56 |
| Number of pages | 4 |
| Journal | Urogynaecologia International Journal |
| Volume | 10 |
| Issue number | 2 |
| Publication status | Published - 1996 |
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Keywords
- desmopressine (DDAVP)
- oxybutynin
- urgency-frequency syndrome
ASJC Scopus subject areas
- Obstetrics and Gynaecology
Cite this
New treatment of urgency-frequency syndrome in female : Oxybutynin bladder instillation and nasal desmopressine (DDAVP). / Mantovani, F.; Patelli, E.; Ceresoli, A.; Seveso, M.
In: Urogynaecologia International Journal, Vol. 10, No. 2, 1996, p. 53-56.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - New treatment of urgency-frequency syndrome in female
T2 - Oxybutynin bladder instillation and nasal desmopressine (DDAVP)
AU - Mantovani, F.
AU - Patelli, E.
AU - Ceresoli, A.
AU - Seveso, M.
PY - 1996
Y1 - 1996
N2 - In painful bladder syndrome of phlogistic outcome, diagnostic assessment is able to distinguish between bacterial and non bacterial cystitis and endoscopy to evaluate the presence of leucoplasic trigonitis. In absence of infection or leucoplasia we propose the following management: bladder instillation (twice a week for a month) with oxybutynin 20 mg in 20 cc of saline solution. Desmopressine (0,2 cc by nasal drops) three hours before irrigation. On 12 patients all were cured at one year follow up even if 40% needed a second treatment. No side effects were described. Urine flow prevents effectiveness of direct administration of drugs in bladder. Oxybutynin is otherwise not long tolerated for well known side effects. The association with DDAVP (Desmopressine) makes the treatment reliable.
AB - In painful bladder syndrome of phlogistic outcome, diagnostic assessment is able to distinguish between bacterial and non bacterial cystitis and endoscopy to evaluate the presence of leucoplasic trigonitis. In absence of infection or leucoplasia we propose the following management: bladder instillation (twice a week for a month) with oxybutynin 20 mg in 20 cc of saline solution. Desmopressine (0,2 cc by nasal drops) three hours before irrigation. On 12 patients all were cured at one year follow up even if 40% needed a second treatment. No side effects were described. Urine flow prevents effectiveness of direct administration of drugs in bladder. Oxybutynin is otherwise not long tolerated for well known side effects. The association with DDAVP (Desmopressine) makes the treatment reliable.
KW - desmopressine (DDAVP)
KW - oxybutynin
KW - urgency-frequency syndrome
UR - http://www.scopus.com/inward/record.url?scp=0029813811&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0029813811&partnerID=8YFLogxK
M3 - Article
VL - 10
SP - 53
EP - 56
JO - Urogynaecologia International Journal
JF - Urogynaecologia International Journal
SN - 1121-3086
IS - 2
ER -