Newly available and recent advances in drug-eluting stents

Charis Costopoulos, Azeem Latib, Toru Naganuma, Alessandro Sticchi, Francesco Giannini, Antonio Colombo

Research output: Contribution to journalArticlepeer-review

Abstract

The introduction of drug-eluting stents has revolutionized the treatment of coronary artery disease. First-generation stents, however, were associated with relatively high revascularization rates and the risk of stent thrombosis. This has led to a worldwide search for improvements in stent technology that will reduce adverse cardiac events following stent implantation while providing optimal treatment. Here, the authors discuss recent advances in stent technology from improvements in stent platform and stent polymer to newer mechanisms of drug delivery and the incorporation of proendothelizing agents. The authors also introduce some of the newly available stents and discuss the evidence associated with their use in clinical practice.

Original languageEnglish
Pages (from-to)555-566
Number of pages12
JournalExpert Review of Cardiovascular Therapy
Volume11
Issue number5
DOIs
Publication statusPublished - May 2013

Keywords

  • bioresorbable stent
  • coronary artery disease
  • drug-eluting stent
  • dual antiplatelet therapy
  • late lumen loss
  • percutaneous coronary intervention
  • polymer
  • stent thrombosis
  • target lesion revascularization

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Internal Medicine

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