@article{6331aede7dc244a881607b5003c51922,
title = "Next-Generation Sequencing Approaches for the Identification of Pathognomonic Fusion Transcripts in Sarcomas: The Experience of the Italian ACC Sarcoma Working Group",
abstract = "This work describes the set-up of a shared platform among the laboratories of the Alleanza Contro il Cancro (ACC) Italian Research Network for the identification of fusion transcripts in sarcomas by using Next Generation Sequencing (NGS). Different NGS approaches, including anchored multiplex PCR and hybrid capture-based panels, were employed to profile a large set of sarcomas of different histotypes. The analysis confirmed the reliability of NGS RNA-based approaches in detecting sarcoma-specific rearrangements. Overall, the anchored multiplex PCR assay proved to be a fast and easy-to-analyze approach for routine diagnostics laboratories.",
author = "D. Racanelli and M. Brenca and D. Baldazzi and F. Goeman and B. Casini and {De Angelis}, B. and M. Guercio and G.M. Milano and E. Tamborini and A. Busico and G. Dagrada and C. Garofalo and C. Caruso and A. Brunello and Y. Pignochino and E. Berrino and G. Grignani and K. Scotlandi and A. Parra and C.M. Hattinger and T. Ibrahim and L. Mercatali and {De Vita}, A. and M.V. Carriero and M. Pallocca and R. Loria and R. Covello and M. Sbaraglia and {Dei Tos}, A.P. and R. Falcioni and R. Maestro",
note = "Cited By :3 Export Date: 18 February 2021",
year = "2020",
doi = "10.3389/fonc.2020.00489",
language = "Italian",
volume = "10",
journal = "Frontiers in Oncology",
issn = "2234-943X",
publisher = "Frontiers Media S. A.",
}