NICU Infants & SNHL: Experience of a western Sicily tertiary care centre

Francesco Gazia, Pietro Abita, Giuseppe Alberti, Sabrina Loteta, Patrizia Longo, Fabrizia Caminiti, Rosalia Gargano

Research output: Contribution to journalArticlepeer-review


Introduction: The variability of symptoms and signs caused by central nervous system (CNS) lesions make multiple sclerosis difficult to recognize,Introduction: This study adds the evaluation of the independent etiologic factors that may play a role in the development of SNHL in a NICU population. We compared neonatal intensive care unit NICU infants with sensorineural hearing loss SNHL to age and gender matched normal hearing NICU controls. Materials and methods: 284 consecutive NICU infants positive to the presence of risk indicators associated with permanent congenital, delayed-onset, or progressive hearing loss underwent to global audiological assessment. The following risk factors were researched, making a distinction between prenatal and perinatal risk factors: in the first group, family history of permanent childhood hearing impairment, consanguinity, pregnant maternal infection and drugs exposition during pregnancy; in the second group, premature birth, respiratory distress, hyperbilirubinemia requiring exchange tranfusion, very low birth weight, cranio-facial abnormality, perinatal infections, ototoxic drugs administration, acidosis, hyponatremia, head trauma. Results: The analysis of the auditory deficit for infants according to numbers of risk factors showed mean values of: 78 + 28.08 dB nHL for infants positive to two risk factors; 75.71 + 30.30 dB nHL in cases positive to three risk factors; 96.66 + 34.46 dB nHL for four risk factors and 85 + 35 dB nHL in case of >5 risk factors. Conclusion: NICU infants have greater chances of developing SNHL, because of the presence of multiple risk factors; in fact, as the number of coexisting risk factors increases, the prevalence rate of SNHL also increases (r=0.81).

Original languageEnglish
Pages (from-to)1001-1007
Number of pages7
JournalActa Medica Mediterranea
Issue number2
Publication statusPublished - Jan 1 2019


  • Infants
  • NICU
  • Risk factors hearing loss

ASJC Scopus subject areas

  • Medicine(all)


Dive into the research topics of 'NICU Infants & SNHL: Experience of a western Sicily tertiary care centre'. Together they form a unique fingerprint.

Cite this