Nitazoxanide or CD3+/CD4+ lymphocytes for recovery from severe Cryptosporidium infection after allogeneic bone marrow transplant?

M. Faraci, B. Cappelli, G. Morreale, E. Lanino, C. Moroni, R. Bandettini, M. P. Terranova, D. Di Martino, C. Coccia, E. Castagnola

Research output: Contribution to journalArticle

Abstract

We describe a case of Cryptosporidium infection occurring in a child after allogeneic SCT for acute non-lymphoblastic leukemia. This patient presented an intestinal, biliar, and pancreatic Cryptosporidium disease associated with an intestinal aGvHD. The increase in CD3+/CD4+ cells secondary to the reduction of steroid therapy associated with the improvement of aGvHD and the use of antiparasitic treatments (especially nitazoxanide) improved the infection-related symptoms and led to a complete clearance of the Cryptosporidium.

Original languageEnglish
Pages (from-to)113-116
Number of pages4
JournalPediatric Transplantation
Volume11
Issue number1
DOIs
Publication statusPublished - Feb 2007

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Keywords

  • Bone marrow transplantation
  • CD3+/CD4+ lymphocytes
  • Cryptosporidium
  • Nitazoxanide

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Transplantation

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