Abstract
A 66-year-old man presented with widespread annular and bullous subacute cutaneous lupus erythematosus (SCLE), developed after starting treatment for hypertension with the calcium channel blocker nitrendipine. A few days after withdrawal of the drug, while cutaneous manifestations were improving, left hemiparesis occurred. Laboratory investigations showed, in addition to anti-Ro, anti-La and anti-histone antibodies, the presence of lupus anticoagulant, anticardiolipin antibodies, prolonged APTT and thrombocytopenia. On the basis of the spontaneous regression of the patient's skin lesions after discontinuation of the drug, a possible relationship between nitrendipine intake, the clinical events and the biological findings is discussed.
| Original language | English |
|---|---|
| Pages (from-to) | 213-216 |
| Number of pages | 4 |
| Journal | European Journal of Dermatology |
| Volume | 13 |
| Issue number | 2 |
| Publication status | Published - Mar 2003 |
Keywords
- Antiphospholipid syndrome
- Drug-induced subacute cutaneous lupus erythematosus
- Nitrendipine
ASJC Scopus subject areas
- Dermatology
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Cite this
Marzano, A. V., Borghi, A., Mercogliano, M., Facchetti, M., & Caputo, R. (2003). Nitrendipine-induced subacute cutaneous lupus erythematosus. European Journal of Dermatology, 13(2), 213-216.