Nitric oxide and histone acetylation - Shaping craniofacial development

Libera Berghella, Pier Lorenzo Puri

Research output: Contribution to journalArticlepeer-review

Abstract

Previous work linked nitric oxide (NO) signaling to histone deacetelyases (HDACs) in the control of tissue homeostasis and suggested that deregulation of this signaling contributes to human diseases. In the previous issue of Chemistry & Biology, Kong and colleagues showed that coordinated NO signaling and histone acetylation are required for proper cranial neural crest development and craniofacial morphogenesis and suggested that alterations of NO/acetylation network can contribute to the pathogenesis of craniofacial malformations.

Original languageEnglish
Pages (from-to)565-566
Number of pages2
JournalChemistry and Biology
Volume21
Issue number5
DOIs
Publication statusPublished - May 22 2014

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Molecular Biology
  • Clinical Biochemistry
  • Molecular Medicine
  • Pharmacology
  • Medicine(all)

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