Abstract
The effects of competitive (2-amino-phosphonovaleric acid) and noncompetitive (Mg2+, ketamine, kynurenic acid) antagonists of N-methyl-D-aspartate (NMDA) receptors on synaptic transmission were studied in afferent synapses of the frog semicircular canals. All of these antagonists reduced the rate of background activity in the nerve of posterior semicircular canal by 30-50%, which confirms the presence of glutamate NMDA receptors in the hair cell synapses in the frog semicircular canals.
| Original language | English |
|---|---|
| Pages (from-to) | 142-143 |
| Number of pages | 2 |
| Journal | Neurophysiology |
| Volume | 25 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - May 1993 |
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ASJC Scopus subject areas
- Neuroscience(all)
- Physiology
Cite this
NMDA receptors in afferent synapses of frog semicircular canals. / Zucca, C.; Akoev, G. N.; Valli, P.; Maracci, A.
In: Neurophysiology, Vol. 25, No. 3, 05.1993, p. 142-143.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - NMDA receptors in afferent synapses of frog semicircular canals
AU - Zucca, C.
AU - Akoev, G. N.
AU - Valli, P.
AU - Maracci, A.
PY - 1993/5
Y1 - 1993/5
N2 - The effects of competitive (2-amino-phosphonovaleric acid) and noncompetitive (Mg2+, ketamine, kynurenic acid) antagonists of N-methyl-D-aspartate (NMDA) receptors on synaptic transmission were studied in afferent synapses of the frog semicircular canals. All of these antagonists reduced the rate of background activity in the nerve of posterior semicircular canal by 30-50%, which confirms the presence of glutamate NMDA receptors in the hair cell synapses in the frog semicircular canals.
AB - The effects of competitive (2-amino-phosphonovaleric acid) and noncompetitive (Mg2+, ketamine, kynurenic acid) antagonists of N-methyl-D-aspartate (NMDA) receptors on synaptic transmission were studied in afferent synapses of the frog semicircular canals. All of these antagonists reduced the rate of background activity in the nerve of posterior semicircular canal by 30-50%, which confirms the presence of glutamate NMDA receptors in the hair cell synapses in the frog semicircular canals.
UR - http://www.scopus.com/inward/record.url?scp=34249766132&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34249766132&partnerID=8YFLogxK
U2 - 10.1007/BF01053139
DO - 10.1007/BF01053139
M3 - Article
AN - SCOPUS:34249766132
VL - 25
SP - 142
EP - 143
JO - Neurophysiology
JF - Neurophysiology
SN - 0090-2977
IS - 3
ER -