NMDA receptors in afferent synapses of frog semicircular canals

C. Zucca; G. N. Akoev; P. Valli; A. Maracci

doi:10.1007/BF01053139

NMDA receptors in afferent synapses of frog semicircular canals

C. Zucca, G. N. Akoev, P. Valli, A. Maracci

Istituto "Eugenio Medea" - Associazione La Nostra Famiglia

Research output: Contribution to journal › Article › peer-review

Abstract

The effects of competitive (2-amino-phosphonovaleric acid) and noncompetitive (Mg²⁺, ketamine, kynurenic acid) antagonists of N-methyl-D-aspartate (NMDA) receptors on synaptic transmission were studied in afferent synapses of the frog semicircular canals. All of these antagonists reduced the rate of background activity in the nerve of posterior semicircular canal by 30-50%, which confirms the presence of glutamate NMDA receptors in the hair cell synapses in the frog semicircular canals.

Original language	English
Pages (from-to)	142-143
Number of pages	2
Journal	Neurophysiology
Volume	25
Issue number	3
DOIs	https://doi.org/10.1007/BF01053139
Publication status	Published - May 1993

ASJC Scopus subject areas

Neuroscience(all)
Physiology

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abstract = "The effects of competitive (2-amino-phosphonovaleric acid) and noncompetitive (Mg2+, ketamine, kynurenic acid) antagonists of N-methyl-D-aspartate (NMDA) receptors on synaptic transmission were studied in afferent synapses of the frog semicircular canals. All of these antagonists reduced the rate of background activity in the nerve of posterior semicircular canal by 30-50%, which confirms the presence of glutamate NMDA receptors in the hair cell synapses in the frog semicircular canals.",

author = "C. Zucca and Akoev, {G. N.} and P. Valli and A. Maracci",

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AU - Valli, P.

AU - Maracci, A.

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