NMDA receptors in afferent synapses of frog semicircular canals

C. Zucca, G. N. Akoev, P. Valli, A. Maracci

Research output: Contribution to journalArticlepeer-review

Abstract

The effects of competitive (2-amino-phosphonovaleric acid) and noncompetitive (Mg2+, ketamine, kynurenic acid) antagonists of N-methyl-D-aspartate (NMDA) receptors on synaptic transmission were studied in afferent synapses of the frog semicircular canals. All of these antagonists reduced the rate of background activity in the nerve of posterior semicircular canal by 30-50%, which confirms the presence of glutamate NMDA receptors in the hair cell synapses in the frog semicircular canals.

Original languageEnglish
Pages (from-to)142-143
Number of pages2
JournalNeurophysiology
Volume25
Issue number3
DOIs
Publication statusPublished - May 1993

ASJC Scopus subject areas

  • Neuroscience(all)
  • Physiology

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