NMDAR encephalitis presenting as akinesia in a patient with Parkinson disease

Matteo Gastaldi, Carla Arbasino, Carlo Dallocchio, Luca Diamanti, Paola Bini, Enrico Marchioni, Diego Franciotta

Research output: Contribution to journalArticle

Abstract

We describe the case of a woman with Parkinson disease who developed an N-methyl-d-aspartate receptor antibody-mediated encephalitis. As a novelty, the encephalitis presentation mimicked a worsening of the pre-existing extrapyramidal syndrome, manifesting mainly as severe bradykinesia and, eventually, akinesia. Brain MRI was normal, whereas cerebrospinal fluid (CSF) analysis disclosed unique-to-CSF oligoclonal bands. Prompt identification and timely immunotherapy led to a complete recovery.

Original languageEnglish
Pages (from-to)35-37
Number of pages3
JournalJournal of Neuroimmunology
Volume328
DOIs
Publication statusPublished - Mar 15 2019

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Encephalitis
Parkinson Disease
Cerebrospinal Fluid
Oligoclonal Bands
Hypokinesia
Immunotherapy
Antibodies
Brain
aspartic acid receptor

Cite this

NMDAR encephalitis presenting as akinesia in a patient with Parkinson disease. / Gastaldi, Matteo; Arbasino, Carla; Dallocchio, Carlo; Diamanti, Luca; Bini, Paola; Marchioni, Enrico; Franciotta, Diego.

In: Journal of Neuroimmunology, Vol. 328, 15.03.2019, p. 35-37.

Research output: Contribution to journalArticle

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AU - Bini, Paola

AU - Marchioni, Enrico

AU - Franciotta, Diego

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