Abstract
We describe the case of a woman with Parkinson disease who developed an N-methyl-d-aspartate receptor antibody-mediated encephalitis. As a novelty, the encephalitis presentation mimicked a worsening of the pre-existing extrapyramidal syndrome, manifesting mainly as severe bradykinesia and, eventually, akinesia. Brain MRI was normal, whereas cerebrospinal fluid (CSF) analysis disclosed unique-to-CSF oligoclonal bands. Prompt identification and timely immunotherapy led to a complete recovery.
| Original language | English |
|---|---|
| Pages (from-to) | 35-37 |
| Number of pages | 3 |
| Journal | Journal of Neuroimmunology |
| Volume | 328 |
| DOIs | |
| Publication status | Published - Mar 15 2019 |
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NMDAR encephalitis presenting as akinesia in a patient with Parkinson disease. / Gastaldi, Matteo; Arbasino, Carla; Dallocchio, Carlo; Diamanti, Luca; Bini, Paola; Marchioni, Enrico; Franciotta, Diego.
In: Journal of Neuroimmunology, Vol. 328, 15.03.2019, p. 35-37.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - NMDAR encephalitis presenting as akinesia in a patient with Parkinson disease
AU - Gastaldi, Matteo
AU - Arbasino, Carla
AU - Dallocchio, Carlo
AU - Diamanti, Luca
AU - Bini, Paola
AU - Marchioni, Enrico
AU - Franciotta, Diego
N1 - Copyright © 2018. Published by Elsevier B.V.
PY - 2019/3/15
Y1 - 2019/3/15
N2 - We describe the case of a woman with Parkinson disease who developed an N-methyl-d-aspartate receptor antibody-mediated encephalitis. As a novelty, the encephalitis presentation mimicked a worsening of the pre-existing extrapyramidal syndrome, manifesting mainly as severe bradykinesia and, eventually, akinesia. Brain MRI was normal, whereas cerebrospinal fluid (CSF) analysis disclosed unique-to-CSF oligoclonal bands. Prompt identification and timely immunotherapy led to a complete recovery.
AB - We describe the case of a woman with Parkinson disease who developed an N-methyl-d-aspartate receptor antibody-mediated encephalitis. As a novelty, the encephalitis presentation mimicked a worsening of the pre-existing extrapyramidal syndrome, manifesting mainly as severe bradykinesia and, eventually, akinesia. Brain MRI was normal, whereas cerebrospinal fluid (CSF) analysis disclosed unique-to-CSF oligoclonal bands. Prompt identification and timely immunotherapy led to a complete recovery.
U2 - 10.1016/j.jneuroim.2018.12.002
DO - 10.1016/j.jneuroim.2018.12.002
M3 - Article
C2 - 30557688
VL - 328
SP - 35
EP - 37
JO - Journal of Neuroimmunology
JF - Journal of Neuroimmunology
SN - 0165-5728
ER -