Abstract
Arinami et al. (1994) reported an association between the Ser311/Cys311 variant of the DRD2 gene and schizophrenia in a Japanese population. We did not find statistically significant differences in the distribution of the allele frequencies between schizophrenics (103) and controls (97) in a case- control sample (χ 2 = 2.07; p = 0.150) or in 64 nuclear families with the haplotype relative risk (HRR) design (χ 2 = 0.13; p=0.718). Our results seem to exclude a main involvement of this variant of the dopamine D2 receptor gene in the etiopathogenesis of schizophrenia.
Original language | English |
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Pages (from-to) | 117-121 |
Number of pages | 5 |
Journal | Schizophrenia Research |
Volume | 25 |
Issue number | 2 |
DOIs | |
Publication status | Published - May 24 1997 |
Keywords
- Association study
- Dopamine D2 receptor gene
- Haplotype relative risk
- Schizophrenia
ASJC Scopus subject areas
- Psychiatry and Mental health
- Behavioral Neuroscience
- Biological Psychiatry
- Neurology
- Psychology(all)