Abstract
Short- and long-term persistence of fetal DNA in maternal plasma has been investigated. Short-term persistence at very low concentration was detected in 47 out of 105 women within two days after delivery. Twelve out of 13 samples re-tested within three days scored negative. No long-term persistence was detected in 172 women who had previous sons or abortions. Molecular micro-chimerism due to circulating fetal DNA persisting from previous pregnancies should not hamper non-invasive plasma-based prenatal testing.
Original language | English |
---|---|
Pages (from-to) | 617-618 |
Number of pages | 2 |
Journal | Human Genetics |
Volume | 112 |
Issue number | 5-6 |
Publication status | Published - May 2003 |
ASJC Scopus subject areas
- Genetics(clinical)
- Genetics