No treatment, resection and ethanol injection in hepatocellular carcinoma

a retrospective analysis of survival in 391 patients with cirrhosis

Tito Livraghi, Luigi Bolondi, Luigi Buscarini, Mario Cottone, Alighieri Mazziotti, Alberto Morabito, Guido Torzilli

Research output: Contribution to journalArticle

274 Citations (Scopus)

Abstract

Background/Aims: This retrospective study was undertaken to obtain information relevant to the therapeutic strategy in single hepatocellular carcinoma associated with Child's A and B cirrhosis. Methods: From a total of 1108 consecutive patients with hepatocellular carcinoma, 391 patients with single, small (≤5 cm) hepatocellular carcinoma (260 in Child A class and 131 in Child B class) were observed: 120 were treated by surgical resection, 155 by percutaneous ethanol injection and 116 were untreated. The end point of the study was 3-year survival. The log rank test was used to compare survival among the different groups. Results: In the Child A group the cumulative 3-year survival was 79% for surgery, 71% for percutaneous ethanol injection and 26% for no treatment (p

Original languageEnglish
Pages (from-to)522-526
Number of pages5
JournalJournal of Hepatology
Volume22
Issue number5
DOIs
Publication statusPublished - 1995

Fingerprint

Survival Analysis
Hepatocellular Carcinoma
Fibrosis
Ethanol
Injections
Survival
Therapeutics
Retrospective Studies

Keywords

  • Liver tumors
  • Natural history
  • Percutaneous ethanol injection
  • Surgery

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

Cite this

No treatment, resection and ethanol injection in hepatocellular carcinoma : a retrospective analysis of survival in 391 patients with cirrhosis. / Livraghi, Tito; Bolondi, Luigi; Buscarini, Luigi; Cottone, Mario; Mazziotti, Alighieri; Morabito, Alberto; Torzilli, Guido.

In: Journal of Hepatology, Vol. 22, No. 5, 1995, p. 522-526.

Research output: Contribution to journalArticle

Livraghi, Tito ; Bolondi, Luigi ; Buscarini, Luigi ; Cottone, Mario ; Mazziotti, Alighieri ; Morabito, Alberto ; Torzilli, Guido. / No treatment, resection and ethanol injection in hepatocellular carcinoma : a retrospective analysis of survival in 391 patients with cirrhosis. In: Journal of Hepatology. 1995 ; Vol. 22, No. 5. pp. 522-526.
@article{f54bc94252fb4a9497629a9a939b1566,
title = "No treatment, resection and ethanol injection in hepatocellular carcinoma: a retrospective analysis of survival in 391 patients with cirrhosis",
abstract = "Background/Aims: This retrospective study was undertaken to obtain information relevant to the therapeutic strategy in single hepatocellular carcinoma associated with Child's A and B cirrhosis. Methods: From a total of 1108 consecutive patients with hepatocellular carcinoma, 391 patients with single, small (≤5 cm) hepatocellular carcinoma (260 in Child A class and 131 in Child B class) were observed: 120 were treated by surgical resection, 155 by percutaneous ethanol injection and 116 were untreated. The end point of the study was 3-year survival. The log rank test was used to compare survival among the different groups. Results: In the Child A group the cumulative 3-year survival was 79{\%} for surgery, 71{\%} for percutaneous ethanol injection and 26{\%} for no treatment (p",
keywords = "Liver tumors, Natural history, Percutaneous ethanol injection, Surgery",
author = "Tito Livraghi and Luigi Bolondi and Luigi Buscarini and Mario Cottone and Alighieri Mazziotti and Alberto Morabito and Guido Torzilli",
year = "1995",
doi = "10.1016/0168-8278(95)80445-5",
language = "English",
volume = "22",
pages = "522--526",
journal = "Journal of Hepatology",
issn = "0168-8278",
publisher = "Elsevier B.V.",
number = "5",

}

TY - JOUR

T1 - No treatment, resection and ethanol injection in hepatocellular carcinoma

T2 - a retrospective analysis of survival in 391 patients with cirrhosis

AU - Livraghi, Tito

AU - Bolondi, Luigi

AU - Buscarini, Luigi

AU - Cottone, Mario

AU - Mazziotti, Alighieri

AU - Morabito, Alberto

AU - Torzilli, Guido

PY - 1995

Y1 - 1995

N2 - Background/Aims: This retrospective study was undertaken to obtain information relevant to the therapeutic strategy in single hepatocellular carcinoma associated with Child's A and B cirrhosis. Methods: From a total of 1108 consecutive patients with hepatocellular carcinoma, 391 patients with single, small (≤5 cm) hepatocellular carcinoma (260 in Child A class and 131 in Child B class) were observed: 120 were treated by surgical resection, 155 by percutaneous ethanol injection and 116 were untreated. The end point of the study was 3-year survival. The log rank test was used to compare survival among the different groups. Results: In the Child A group the cumulative 3-year survival was 79% for surgery, 71% for percutaneous ethanol injection and 26% for no treatment (p

AB - Background/Aims: This retrospective study was undertaken to obtain information relevant to the therapeutic strategy in single hepatocellular carcinoma associated with Child's A and B cirrhosis. Methods: From a total of 1108 consecutive patients with hepatocellular carcinoma, 391 patients with single, small (≤5 cm) hepatocellular carcinoma (260 in Child A class and 131 in Child B class) were observed: 120 were treated by surgical resection, 155 by percutaneous ethanol injection and 116 were untreated. The end point of the study was 3-year survival. The log rank test was used to compare survival among the different groups. Results: In the Child A group the cumulative 3-year survival was 79% for surgery, 71% for percutaneous ethanol injection and 26% for no treatment (p

KW - Liver tumors

KW - Natural history

KW - Percutaneous ethanol injection

KW - Surgery

UR - http://www.scopus.com/inward/record.url?scp=0029027614&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029027614&partnerID=8YFLogxK

U2 - 10.1016/0168-8278(95)80445-5

DO - 10.1016/0168-8278(95)80445-5

M3 - Article

VL - 22

SP - 522

EP - 526

JO - Journal of Hepatology

JF - Journal of Hepatology

SN - 0168-8278

IS - 5

ER -