No treatment, resection and ethanol injection in hepatocellular carcinoma: a retrospective analysis of survival in 391 patients with cirrhosis

Tito Livraghi, Luigi Bolondi, Luigi Buscarini, Mario Cottone, Alighieri Mazziotti, Alberto Morabito, Guido Torzilli

Research output: Contribution to journalArticle


Background/Aims: This retrospective study was undertaken to obtain information relevant to the therapeutic strategy in single hepatocellular carcinoma associated with Child's A and B cirrhosis. Methods: From a total of 1108 consecutive patients with hepatocellular carcinoma, 391 patients with single, small (≤5 cm) hepatocellular carcinoma (260 in Child A class and 131 in Child B class) were observed: 120 were treated by surgical resection, 155 by percutaneous ethanol injection and 116 were untreated. The end point of the study was 3-year survival. The log rank test was used to compare survival among the different groups. Results: In the Child A group the cumulative 3-year survival was 79% for surgery, 71% for percutaneous ethanol injection and 26% for no treatment (p

Original languageEnglish
Pages (from-to)522-526
Number of pages5
JournalJournal of Hepatology
Issue number5
Publication statusPublished - 1995



  • Liver tumors
  • Natural history
  • Percutaneous ethanol injection
  • Surgery

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

Cite this