Nocturnal desaturations in COPD: Still an open question?

Research output: Contribution to journalArticlepeer-review

Abstract

The relevance of sleep oxyhemoglobin desaturations in COPD patients is still a matter of debate. The best definition for clinical outcomes is the occurrence of episodes lasting at least 5 minutes and reaching SaO2 levels less than or equal to 85%. Focusing on longer and milder episodes (at least 30% of the night with SaO2 <90%) did not provide clinical relevance. One possible consequence of desaturation episodes could be a worsening of pulmonary hemodynamics, but O2 dips could just be a marker of a mechanical derangement associated with a worse prognosis. Data confirming the association of these episodes with the clinical type of COPD and with inflammatory mediator modulation are still lacking.

Original languageEnglish
Pages (from-to)25-26
Number of pages2
JournalSleep and Breathing
Volume6
Issue number1
DOIs
Publication statusPublished - 2002

Keywords

  • COPD
  • Long-term oxygen therapy
  • Sleep desaturations

ASJC Scopus subject areas

  • Otorhinolaryngology

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