Nocturnal oximetry in infants with cystic fibrosis

M. P. Villa, J. Pagani, V. Lucidi, S. Palamides, R. Ronchetti

Research output: Contribution to journalArticlepeer-review

Abstract

Aim - To investigate whether children with cystic fibrosis under 3 years of age have disordered breathing and episodes of oxygen desaturation during sleep. Methods - We studied 19 infants (9 boys and 10 girls) with cystic fibrosis, mean age 13.1 months (range 3-36 months) and 20 age and sex matched healthy subjects. Patients and controls underwent an over-night polysomnographic study and respiratory function testing on the following morning. Results - Seven patients with ongoing respiratory tract inflammation had disordered breathing and episodes of oxygen desaturation during sleep. Pulse oximetry showed a significantly lower mean oxygen saturation (Sao2) and a higher percentage of total sleep time spent with Sao2 less than 93% in symptomatic children than in controls. Conclusion - Results suggest that infants and young children with cystic fibrosis and mild airways inflammation (rhinitis, cough, red throat) have episodes of oxygen desaturation during sleep.

Original languageEnglish
Pages (from-to)50-54
Number of pages5
JournalArchives of Disease in Childhood
Volume84
Issue number1
DOIs
Publication statusPublished - 2001

Keywords

  • Cystic fibrosis
  • Oxygen desaturation
  • Sleep

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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