TY - JOUR
T1 - Nocturnal paroxysmal arousals with motor behaviors during sleep
T2 - Frontal lobe epilepsy or parasomnia?
AU - Zucconi, Marco
AU - Oldani, Alessandro
AU - Ferini-Strambi, Luigi
AU - Bizzozero, Daniele
AU - Smirne, Salvatore
PY - 1997
Y1 - 1997
N2 - Nocturnal paroxysmal arousals with motor behaviors have been described in a few individuals, and their possible epileptic origin as nocturnal frontal lobe seizures has been suggested. However, the clinical and polysomnographic differentiation from parasomnias and physiologic movements during sleep have not been clarified yet. In this study, we evaluated a group of patients with nocturnal motor behaviors and tried to characterize paroxysmal arousals. Thirty-four participants (mean [±SD] age 22.7 [±12.9] years) noting nocturnal motor agitation or behaviors and 12 healthy controls (mean age 24.1 [±3.1] years) underwent nocturnal polysomnography with video- tape recording and motor behaviors analysis. Arousals with motor attacks were classified as minimal, minor, or major depending on semiology, complexity, and duration of behaviors. All patients showed several minimal (e.g., scratching or rubbing the nose and the head) and minor (e.g., pelvic thrusting or swinging with dystonic component) attacks, and 53% also had major episodes (e.g., sudden elevation of the head and trunk from the bed with complex behaviors) occurring mainly in non-rapid eye movement sleep. In all the patients, motor attacks were characterized by stereotypy, sudden onset, short duration, and repetitiveness. In 80%, epileptiform abnormalities were found. All control subjects showed motor events, but they were fewer, slower, nonstereotyped, and semiologically different from the patients'. No significant difference in conventional sleep parameters between the two groups were found. Paroxysmal arousals with motor behaviors probably represent a particular form of nocturnal frontal lobe epilepsy rather than an unusual parasomnia. The semiologic characteristics of these type of arousals are difficult to recognize and differentiate from physiologic movements or parasomnias without video-polygraphic analysis.
AB - Nocturnal paroxysmal arousals with motor behaviors have been described in a few individuals, and their possible epileptic origin as nocturnal frontal lobe seizures has been suggested. However, the clinical and polysomnographic differentiation from parasomnias and physiologic movements during sleep have not been clarified yet. In this study, we evaluated a group of patients with nocturnal motor behaviors and tried to characterize paroxysmal arousals. Thirty-four participants (mean [±SD] age 22.7 [±12.9] years) noting nocturnal motor agitation or behaviors and 12 healthy controls (mean age 24.1 [±3.1] years) underwent nocturnal polysomnography with video- tape recording and motor behaviors analysis. Arousals with motor attacks were classified as minimal, minor, or major depending on semiology, complexity, and duration of behaviors. All patients showed several minimal (e.g., scratching or rubbing the nose and the head) and minor (e.g., pelvic thrusting or swinging with dystonic component) attacks, and 53% also had major episodes (e.g., sudden elevation of the head and trunk from the bed with complex behaviors) occurring mainly in non-rapid eye movement sleep. In all the patients, motor attacks were characterized by stereotypy, sudden onset, short duration, and repetitiveness. In 80%, epileptiform abnormalities were found. All control subjects showed motor events, but they were fewer, slower, nonstereotyped, and semiologically different from the patients'. No significant difference in conventional sleep parameters between the two groups were found. Paroxysmal arousals with motor behaviors probably represent a particular form of nocturnal frontal lobe epilepsy rather than an unusual parasomnia. The semiologic characteristics of these type of arousals are difficult to recognize and differentiate from physiologic movements or parasomnias without video-polygraphic analysis.
KW - Motor behaviors during sleep
KW - Nocturnal frontal lobe epilepsy
KW - Paroxysmal arousals
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U2 - 10.1097/00004691-199711000-00008
DO - 10.1097/00004691-199711000-00008
M3 - Article
C2 - 9458058
AN - SCOPUS:0031398297
VL - 14
SP - 513
EP - 522
JO - Journal of Clinical Neurophysiology
JF - Journal of Clinical Neurophysiology
SN - 0736-0258
IS - 6
ER -