Nodal and extranodal soft tissue polymorphous hemangioendothelioma: A case report and review of the literature

Jessica Falleti, Maria Siano, Rossella De Cecio, Anna Somma, Guido Pettinato, Luigi Insabato

Research output: Contribution to journalArticlepeer-review

Abstract

Background. Polymorphous hemangioendothelioma is a rare vascular tumor of borderline malignant potential and only 10 cases have been described in the literature so far. Methods and results. We report a case of nodal and extranodal polymorphous hemangioendothelioma and review the literature. A 66-year-old man with an unremarkable past medical history was admitted for a left submandibular mass. The main nodule was composed of angiosarcoma-like areas mixed with angiomatous features; some vascular spaces with hobnail endothelium were seen. The tumor involved two adjacent lymph nodes. Immunohistochemically, the neoplastic cells were strongly positive for CD31 and vimentin. After a few months the tumor recurred and the patient was treated with radiation therapy. Conclusions. Polymorphous hemangioendothelioma is a distinct entity in the hemangioendothelioma group with its own clinical and histological features.

Original languageEnglish
Pages (from-to)94-97
Number of pages4
JournalTumori
Volume95
Issue number1
Publication statusPublished - Jan 2009

Keywords

  • Hemangioendothelioma
  • Lymph node
  • Polymorphous
  • Vascular tumors

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Fingerprint Dive into the research topics of 'Nodal and extranodal soft tissue polymorphous hemangioendothelioma: A case report and review of the literature'. Together they form a unique fingerprint.

Cite this