Nodular fasciitis of the cervical region: Case report and literature review

Maurizio Cavallini, Riccardo Gazzola, Giovanni Fellegara, Luca Vaienti

Research output: Contribution to journalArticlepeer-review


Nodular fasciitis is a benign proliferation of fibroblasts that commonly occurs in the subcutaneous tissues of the upper extremities and rarely in the musculoskeletal system (muscles, periosteal and articulations), glandular tissue and viscera In this article we describe the case of a 32 year-old woman affected by nodular fasciitis of the cervical region. The ultrasonography exhibited unclear findings and removal was indicated. Although rare, nodular fasciitis should be always kept in account by the practitioner employed in dermatologie surgery. The findings at Ultrasonography and Magnetic Resonance Imaging may mislead the diagnosis due to the features of malignancy that could be usually observed in these cases. Moreover the clinical presentation is usually asymptomatic and aspecific. Few symptoms could arise in case of larger lesions for compression of adjacent structures, although these lesions are usually small (<5 cm) and with slow growth. The microscopic appearance of nodular fasciitis is various and diagnosis is driven by few and aspecific findings. Moreover no specific immunohistochemical markers were available, except for the USP6 gene rearrangement with MYH9 gene that was recently identified. These lesions could be removed surgically or treated conservatively if a microscopic diagnosis has been previously achieved. A prompt diagnosis and surgical approach is often essential for the correct diagnosis, to differentiate this lesion from aggressive sarcomas, therefore being crucial for the surgeon involved in dermatologie surgery.

Original languageEnglish
Pages (from-to)209-212
Number of pages4
JournalJournal of Plastic Dermatology
Issue number3
Publication statusPublished - 2013


  • Fibroblast
  • Fibromatosis
  • Nodular fascitis
  • Nodule
  • Subcutaneous

ASJC Scopus subject areas

  • Dermatology


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