Nodular lymphoma eventuating into lymphoplasmocytic lymphoma with monoclonal IgM/λ cold agglutinin and bence-jones proteinuria

E. Pascali, A. Pezzoli, M. Melato, G. Falconieri

Research output: Contribution to journalArticle

Abstract

A case of nodular lymphocytic (centroblastic/centrocytic) lymphoma that developed within 5 months after the initial diagnosis of lymphoplasmocytic lymphoma is described. The change in the histopathological picture, consisting of the development of a functionally more differentiated B cell neoplasm, occurred in the abdominal lymph nodes while the original pattern persisted in the bone marrow, liver and spleen. The patient was also found to have a serum IgM/ λ monoclonal immunoglobulin exhibiting cold agglutinin activity with specificity for the ‘non-I’ erythrocyte antigens.

Original languageEnglish
Pages (from-to)94-102
Number of pages9
JournalActa Haematologica
Volume64
Issue number2
DOIs
Publication statusPublished - 1980

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Keywords

  • Cold agglutinins
  • Lymphoplasmocytic lymphoma
  • Monoclonal gammopathy
  • Nodular lymphoma

ASJC Scopus subject areas

  • Hematology

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