Nodular sclerosing Hodgkin's disease and large cell lymphoma. Immunophenotypic characterization of a composite case

M. Paulli, R. Rosso, S. Kindl, E. Boveri, M. Sirchi, A. De Medici, R. Invernizzi, U. Magrini

Research output: Contribution to journalArticle


Composite lymphomas have rarely been reported in Hodgkin's disease (HD), except in the lymphocyte predominance sub-type, and immunohistochemical investigations have been performed in only few cases. We describe the histological and immunophenotypical findings in a case of composite nodular sclerosing HD and high-grade, large cell non-Hodgkin's lymphoma (NHL). In our case HD and NHL cells displayed striking morphological and immunophenotypical divergence, suggesting a lack of correlation between the two neoplasms.

Original languageEnglish
Pages (from-to)271-275
Number of pages5
JournalVirchows Archiv A Pathological Anatomy and Histopathology
Issue number3
Publication statusPublished - May 1992



  • Composite lymphoma
  • Hodgkin's disease
  • Immunohistochemistry
  • Non-Hodgkin's lymphoma

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Anatomy

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