Non-clinical tests for the diagnosis of multiple sclerosis.

P. M. Rossini; M. Caramia; F. Lavaroni; M. Spadaro; R. Floris; G. Tanfani; F. Zarola; R. Traversa; M. G. Marciani; G. Bernardi

Non-clinical tests for the diagnosis of multiple sclerosis.

P. M. Rossini, M. Caramia, F. Lavaroni, M. Spadaro, R. Floris, G. Tanfani, F. Zarola, R. Traversa, M. G. Marciani, G. Bernardi

Research output: Contribution to journal › Article › peer-review

Abstract

Liquoral, Neurophysiological and Nuclear Imaging data were investigated in 29 patients suffering from Definite (11 cases), Probable (11 cases) and Possible (7 cases) Multiple Sclerosis (MS). The most sensitive tests were: Visual Evoked Potentials (VEPs), altered in 75% of patients, Motor Evoked Potentials (MEPs), abnormal in 75%, Nuclear Magnetic Resonance Imaging (MRI) in 72.4%. Somatosensory Evoked Potentials (SEPs) were altered in 69.2% in PN-SEPs and in 53.6% in MN-SEPs, whilst Brainstem Evoked Potentials (BAEPs) were altered in 30.8% of cases. The results suggest that patients with suspected forms of MS should be submitted, as routine diagnostic protocol, to a battery of EPs, including as a first choice VEPs, MEPs and PN-SEPs. MRI should be performed to confirm a diagnosis not supported by EP data, or for a comprehensive localization of the demyelinating plaques.

Original language	English
Pages (from-to)	33-40
Number of pages	8
Journal	Rivista di Neurologia
Volume	57
Issue number	1
Publication status	Published - Jan 1987

ASJC Scopus subject areas

Clinical Neurology

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title = "Non-clinical tests for the diagnosis of multiple sclerosis.",

abstract = "Liquoral, Neurophysiological and Nuclear Imaging data were investigated in 29 patients suffering from Definite (11 cases), Probable (11 cases) and Possible (7 cases) Multiple Sclerosis (MS). The most sensitive tests were: Visual Evoked Potentials (VEPs), altered in 75% of patients, Motor Evoked Potentials (MEPs), abnormal in 75%, Nuclear Magnetic Resonance Imaging (MRI) in 72.4%. Somatosensory Evoked Potentials (SEPs) were altered in 69.2% in PN-SEPs and in 53.6% in MN-SEPs, whilst Brainstem Evoked Potentials (BAEPs) were altered in 30.8% of cases. The results suggest that patients with suspected forms of MS should be submitted, as routine diagnostic protocol, to a battery of EPs, including as a first choice VEPs, MEPs and PN-SEPs. MRI should be performed to confirm a diagnosis not supported by EP data, or for a comprehensive localization of the demyelinating plaques.",

author = "Rossini, {P. M.} and M. Caramia and F. Lavaroni and M. Spadaro and R. Floris and G. Tanfani and F. Zarola and R. Traversa and Marciani, {M. G.} and G. Bernardi",

year = "1987",

month = jan,

language = "English",

volume = "57",

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T1 - Non-clinical tests for the diagnosis of multiple sclerosis.

AU - Rossini, P. M.

AU - Caramia, M.

AU - Lavaroni, F.

AU - Spadaro, M.

AU - Floris, R.

AU - Tanfani, G.

AU - Zarola, F.

AU - Traversa, R.

AU - Marciani, M. G.

AU - Bernardi, G.

PY - 1987/1

Y1 - 1987/1

N2 - Liquoral, Neurophysiological and Nuclear Imaging data were investigated in 29 patients suffering from Definite (11 cases), Probable (11 cases) and Possible (7 cases) Multiple Sclerosis (MS). The most sensitive tests were: Visual Evoked Potentials (VEPs), altered in 75% of patients, Motor Evoked Potentials (MEPs), abnormal in 75%, Nuclear Magnetic Resonance Imaging (MRI) in 72.4%. Somatosensory Evoked Potentials (SEPs) were altered in 69.2% in PN-SEPs and in 53.6% in MN-SEPs, whilst Brainstem Evoked Potentials (BAEPs) were altered in 30.8% of cases. The results suggest that patients with suspected forms of MS should be submitted, as routine diagnostic protocol, to a battery of EPs, including as a first choice VEPs, MEPs and PN-SEPs. MRI should be performed to confirm a diagnosis not supported by EP data, or for a comprehensive localization of the demyelinating plaques.

AB - Liquoral, Neurophysiological and Nuclear Imaging data were investigated in 29 patients suffering from Definite (11 cases), Probable (11 cases) and Possible (7 cases) Multiple Sclerosis (MS). The most sensitive tests were: Visual Evoked Potentials (VEPs), altered in 75% of patients, Motor Evoked Potentials (MEPs), abnormal in 75%, Nuclear Magnetic Resonance Imaging (MRI) in 72.4%. Somatosensory Evoked Potentials (SEPs) were altered in 69.2% in PN-SEPs and in 53.6% in MN-SEPs, whilst Brainstem Evoked Potentials (BAEPs) were altered in 30.8% of cases. The results suggest that patients with suspected forms of MS should be submitted, as routine diagnostic protocol, to a battery of EPs, including as a first choice VEPs, MEPs and PN-SEPs. MRI should be performed to confirm a diagnosis not supported by EP data, or for a comprehensive localization of the demyelinating plaques.

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