Non-familial hemophagocytic lymphohistiocytosis

C. Cozzutto, A. Carbone, A. Comelli, R. Volpe

Research output: Contribution to journalArticle

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Abstract

A case of non-familial hemophagocytic lymphohistiocytosis (HLH) is described. The patient had a chronic course being alive and doing relatively well 3 years since onset. The specific pathological features of this disorder are discussed with emphasis on the fact that a remarkable loss of lymph node structure is sustained by a mature lymphohistiocytic infiltrate. Erythrophagocytosis is assessed as an important but not specific finding. Lymphocyte depletion is an important feature of the lesion. The presence of overlapping features in HLH, infection-associated hemophagocytic syndrome (IAHS) and X-linked recessive lymphoproliferative syndrome (XLS) is emphasized.

Original languageEnglish
Pages (from-to)273-278
Number of pages6
JournalPathology Research and Practice
Volume184
Issue number3
Publication statusPublished - 1989

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Hemophagocytic Lymphohistiocytosis
Lymphocyte Depletion
Lymphoproliferative Disorders
Lymph Nodes

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Cozzutto, C., Carbone, A., Comelli, A., & Volpe, R. (1989). Non-familial hemophagocytic lymphohistiocytosis. Pathology Research and Practice, 184(3), 273-278.

Non-familial hemophagocytic lymphohistiocytosis. / Cozzutto, C.; Carbone, A.; Comelli, A.; Volpe, R.

In: Pathology Research and Practice, Vol. 184, No. 3, 1989, p. 273-278.

Research output: Contribution to journalArticle

Cozzutto, C, Carbone, A, Comelli, A & Volpe, R 1989, 'Non-familial hemophagocytic lymphohistiocytosis', Pathology Research and Practice, vol. 184, no. 3, pp. 273-278.
Cozzutto C, Carbone A, Comelli A, Volpe R. Non-familial hemophagocytic lymphohistiocytosis. Pathology Research and Practice. 1989;184(3):273-278.
Cozzutto, C. ; Carbone, A. ; Comelli, A. ; Volpe, R. / Non-familial hemophagocytic lymphohistiocytosis. In: Pathology Research and Practice. 1989 ; Vol. 184, No. 3. pp. 273-278.
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