Abstract
A case of non-familial hemophagocytic lymphohistiocytosis (HLH) is described. The patient had a chronic course being alive and doing relatively well 3 years since onset. The specific pathological features of this disorder are discussed with emphasis on the fact that a remarkable loss of lymph node structure is sustained by a mature lymphohistiocytic infiltrate. Erythrophagocytosis is assessed as an important but not specific finding. Lymphocyte depletion is an important feature of the lesion. The presence of overlapping features in HLH, infection-associated hemophagocytic syndrome (IAHS) and X-linked recessive lymphoproliferative syndrome (XLS) is emphasized.
Original language | English |
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Pages (from-to) | 273-278 |
Number of pages | 6 |
Journal | Pathology Research and Practice |
Volume | 184 |
Issue number | 3 |
Publication status | Published - 1989 |
ASJC Scopus subject areas
- Pathology and Forensic Medicine