Non-Hodgkin lymphomas of the central nervous system.

F. Pisani, M. Antimi, M. Cantonetti, M. G. Marciani, M. Masi, M. Tribalto, G. Papa

Research output: Contribution to journalArticle

Abstract

Non-Hodgkin lymphomas (NHL) of the Central Nervous System (CNS) are rare but they nonetheless constitute a clinical, biological and therapeutic problem of great interest. Primary lymphomas of the CNS account for 2% of all malignant lymphomas and for 0.3-1.5% of all intracranial tumors. Surgery and radiotherapy afford only poor control of the disease. The most satisfactory results have been achieved with combination therapy, surgery + radiotherapy + chemotherapy, but the optimal combination has still to be devised. Secondary neuromeningeal involvement affects a fair number of patients with systemic NHL. The symptoms are broadly the same as in CNS NHL and the treatment as problematic. There have recently been suggestions that the onset of CNS NHL may be exacerbated by immunodeficiency states such as occur in patients who have undergone organ transplantation, in autoimmune disease and, still more recently, in the acquired immunodeficiency syndrome (AIDS). The frequency of these tumors is anyway on the increase and a better insight into the disease in essential.

Original languageEnglish
Pages (from-to)453-459
Number of pages7
JournalItalian Journal of Neurological Sciences
Volume12
Issue number5
Publication statusPublished - Oct 1991

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Non-Hodgkin's Lymphoma
Central Nervous System
Lymphoma
Radiotherapy
Organ Transplantation
Combination Drug Therapy
Autoimmune Diseases
Neoplasms
Acquired Immunodeficiency Syndrome
Therapeutics

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Pisani, F., Antimi, M., Cantonetti, M., Marciani, M. G., Masi, M., Tribalto, M., & Papa, G. (1991). Non-Hodgkin lymphomas of the central nervous system. Italian Journal of Neurological Sciences, 12(5), 453-459.

Non-Hodgkin lymphomas of the central nervous system. / Pisani, F.; Antimi, M.; Cantonetti, M.; Marciani, M. G.; Masi, M.; Tribalto, M.; Papa, G.

In: Italian Journal of Neurological Sciences, Vol. 12, No. 5, 10.1991, p. 453-459.

Research output: Contribution to journalArticle

Pisani, F, Antimi, M, Cantonetti, M, Marciani, MG, Masi, M, Tribalto, M & Papa, G 1991, 'Non-Hodgkin lymphomas of the central nervous system.', Italian Journal of Neurological Sciences, vol. 12, no. 5, pp. 453-459.
Pisani F, Antimi M, Cantonetti M, Marciani MG, Masi M, Tribalto M et al. Non-Hodgkin lymphomas of the central nervous system. Italian Journal of Neurological Sciences. 1991 Oct;12(5):453-459.
Pisani, F. ; Antimi, M. ; Cantonetti, M. ; Marciani, M. G. ; Masi, M. ; Tribalto, M. ; Papa, G. / Non-Hodgkin lymphomas of the central nervous system. In: Italian Journal of Neurological Sciences. 1991 ; Vol. 12, No. 5. pp. 453-459.
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