Non-Hodgkin's lymphoma in a patient with follicular thyroid cancer: The role of 99mTc-methoxy isobutyl isonitrile imaging

S. Maurea; S. Lastoria; M. Klain; L. Celentano; M. Salvatore

Non-Hodgkin's lymphoma in a patient with follicular thyroid cancer: The role of ^99mTc-methoxy isobutyl isonitrile imaging

S. Maurea, S. Lastoria, M. Klain, L. Celentano, M. Salvatore

Research output: Contribution to journal › Article

Abstract

In the post-surgical follow-up of a patient with follicular thyroid carcinoma, a palpable mass in the left supraclavicular region was highly indicative of metastatic disease. Technetium-99m methoxy isobutyl isonitrile (^99mTc-MIBI) showed an increased but heterogeneous uptake within the lesion. Surprisingly, a different neoplastic disease was histologically demonstrated. Lymph node abnormalities due to non-Hodgkin's lymphoma rather than metastatic thyroid disease were demonstrated. In conclusion, non-Hodgkin's lymphoma may occur in patients with follicular thyroid carcinoma. This new lesion significantly concentrated ^99mTc-MIBI. Thus, the results of ^99mTc-MIBI imaging have to be carefully evaluated during the follow-up of patients with thyroid cancer.

Original language	English
Pages (from-to)	18-21
Number of pages	4
Journal	Journal of nuclear biology and medicine (Turin, Italy : 1991)
Volume	38
Issue number	1
Publication status	Published - 1994

Keywords

Tc-MIBI
lymphoma
non-Hodgkin
thyroid neoplasms

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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Maurea, S., Lastoria, S., Klain, M., Celentano, L., & Salvatore, M. (1994). Non-Hodgkin's lymphoma in a patient with follicular thyroid cancer: The role of ^99mTc-methoxy isobutyl isonitrile imaging. Journal of nuclear biology and medicine (Turin, Italy : 1991), 38(1), 18-21.

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AB - In the post-surgical follow-up of a patient with follicular thyroid carcinoma, a palpable mass in the left supraclavicular region was highly indicative of metastatic disease. Technetium-99m methoxy isobutyl isonitrile (99mTc-MIBI) showed an increased but heterogeneous uptake within the lesion. Surprisingly, a different neoplastic disease was histologically demonstrated. Lymph node abnormalities due to non-Hodgkin's lymphoma rather than metastatic thyroid disease were demonstrated. In conclusion, non-Hodgkin's lymphoma may occur in patients with follicular thyroid carcinoma. This new lesion significantly concentrated 99mTc-MIBI. Thus, the results of 99mTc-MIBI imaging have to be carefully evaluated during the follow-up of patients with thyroid cancer.

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