Non-Hodgkin's lymphoma in a patient with follicular thyroid cancer: The role of 99mTc-methoxy isobutyl isonitrile imaging

S. Maurea, S. Lastoria, M. Klain, L. Celentano, M. Salvatore

Research output: Contribution to journalArticlepeer-review


In the post-surgical follow-up of a patient with follicular thyroid carcinoma, a palpable mass in the left supraclavicular region was highly indicative of metastatic disease. Technetium-99m methoxy isobutyl isonitrile (99mTc-MIBI) showed an increased but heterogeneous uptake within the lesion. Surprisingly, a different neoplastic disease was histologically demonstrated. Lymph node abnormalities due to non-Hodgkin's lymphoma rather than metastatic thyroid disease were demonstrated. In conclusion, non-Hodgkin's lymphoma may occur in patients with follicular thyroid carcinoma. This new lesion significantly concentrated 99mTc-MIBI. Thus, the results of 99mTc-MIBI imaging have to be carefully evaluated during the follow-up of patients with thyroid cancer.

Original languageEnglish
Pages (from-to)18-21
Number of pages4
JournalJournal of nuclear biology and medicine (Turin, Italy : 1991)
Issue number1
Publication statusPublished - 1994


  • Tc-MIBI
  • lymphoma
  • non-Hodgkin
  • thyroid neoplasms

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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