Non-Hodgkin's lymphoma mimicking gynecological malignancies of the vagina and cervix: A report of four cases

D. E. Cohn, K. E. Resnick, L. A. Eaton, J. DeHart, V. Zanagnolo

Research output: Contribution to journalArticlepeer-review

Abstract

Although in the past two decades there has been a sharp rise in the incidence of extranodal primary lymphomas in the United States, non-Hodgkin's lymphoma (NHL) of the female genital tract is still rare. We present four cases of extranodal NHL presenting with signs and symptoms consistent with cancer of the vagina or cervix and lacking the "B" symptoms often associated with systemic lymphoma such as fever, weight loss, night sweat, and fatigue. It is important for gynecologists to be aware of this neoplastic disease and to include cervical or vaginal lymphoma in the differential diagnosis of patients presenting with examinations suggestive of cervical or vaginal cancer. A correct diagnosis leads to the appropriate therapy, and radical gynecological surgery can be avoided for primary cervical and vaginal lymphoma.

Original languageEnglish
Pages (from-to)274-279
Number of pages6
JournalInternational Journal of Gynecological Cancer
Volume17
Issue number1
DOIs
Publication statusPublished - Jan 2007

Keywords

  • Cervical and vaginal cancer
  • Crush artifact
  • Non-Hodgkin's lymphoma

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Oncology
  • Cancer Research

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