Non-Hodgkin's lymphoma (NHL) of the oral cavity

Paolo Pecorari, Mauro Melato

Research output: Contribution to journalArticlepeer-review


Background: the treatment of NHL in the head and neck region is complex because of the numerous variables that are involved. Reports in the recent literature on NHL of the oral region have dealt with one or two individual cases and routine treatment guidlines do not exist. Local lesions are responsive to radiotherapy as well as to chemotherapy, but the cure rates are discouragingly low. Patient and methods: we report a case of a painful swelling of the lower left gingiva. Local biopsy and a systemic work-up (labs, x-rays, eco scan, CT, bone marrow aspiration and biopsy) was performed. Results: the biopsy of the oral lesion disclosed a malignant NHL; other examinations failed to find other foci of the lymphomatous process. Conclusions: this case of primitive NHL of the oral cavity summarises the main characteristics of this rather uncommon pathology: a) difficult diagnosis at presentation, often misdiagnosed for other more common oral diseases b) the importance of a local biopsy; c) rapid evolution; d) a good response to chemotherapy; e) poor prognosis.

Original languageEnglish
Pages (from-to)1299-1302
Number of pages4
JournalAnticancer Research
Issue number2 B
Publication statusPublished - Mar 1998


  • Non-Hodgkin's lymphoma
  • Oral cavity
  • Therapy of neck-head cancer

ASJC Scopus subject areas

  • Cancer Research
  • Oncology


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