Abstract
Hydrops fetalis is an excessive accumulation of fetal fluid. Hydrops is traditionally classified into either immune or non-immune hydrops (NIHF), but in practice, nowadays in the Western world >90% of hydrops is of non-immune origin. The basis of the disorder is an imbalance in the regulation of fetal fluid movement between the vascular and interstitial space. We previously suggested a diagnostic flow-chart for NIHF. In this short review we describe the main mechanisms leading to NIHF.
Original language | English |
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Pages (from-to) | 597-605 |
Number of pages | 9 |
Journal | American Journal of Medical Genetics, Part A |
Volume | 158 A |
Issue number | 3 |
DOIs | |
Publication status | Published - Mar 2012 |
Keywords
- Edema of the fetus
- Fetal hydrops
- NIHF
- Non-immune hydrops fetalis
- Pathogenesis
- Pathophysiologic pathways
ASJC Scopus subject areas
- Genetics(clinical)
- Genetics