Non-invasive assessment of Neuromuscular Disorders by 7 tesla Magnetic Resonance Imaging and Spectroscopy: Dedicated radio-frequency coil development

Alessandra Retico, Riccardo Stara, Maria Evelina Fantacci, Alessandra Toncelli, Angelo Galante, Tiziana M. Florio, Marcello Alecci, Mirco Cosottini, Guja Astrea, Roberta Battini, Gianluigi Tiberi, Mauro Costagli, Michela Tosetti

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Magnetic Resonance (MR) Imaging and Spectroscopy of the muscle is a valuable tool in the diagnosis and monitoring of Neuromuscular Disorders (NMD). New Ultra-High Field (UHF) 7 T MRI systems, with their enhanced Signal-to-Noise Ratio, may offer increased image quality in terms of spatial resolution and/or shorter scanning time compared to lower field systems. In the study of NMD the new features provided by UHF MR may allow the use of functional techniques to improve biochemical and physiological information of skeletal muscle correlated to the pathogenesis and progression of the muscle involvement. This study reports the recent achievements in muscle imaging and spectroscopy obtained at the first Italian 7 T MR scanner available at the IMAGO7 Foundation (Pisa, Italy). Dedicated radio-frequency coils for proton imaging and phosphorous spectroscopy have been designed, developed and validated in vivo, and are now ready for clinical research studies.

Original languageEnglish
Title of host publication2015 IEEE International Symposium on Medical Measurements and Applications, MeMeA 2015 - Proceedings
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages68-73
Number of pages6
ISBN (Print)9781479964765
DOIs
Publication statusPublished - Jun 30 2015
Event2015 IEEE International Symposium on Medical Measurements and Applications, MeMeA 2015 - Torino, Italy
Duration: May 7 2015May 9 2015

Other

Other2015 IEEE International Symposium on Medical Measurements and Applications, MeMeA 2015
CountryItaly
CityTorino
Period5/7/155/9/15

Keywords

  • Magnetic Resonance Imaging (MRI)
  • Magnetic Resonance Spectroscopy (MRS)
  • Neuromuscular disorders
  • radio-frequency coils
  • ultrahigh field MRI

ASJC Scopus subject areas

  • Biomedical Engineering
  • Computer Science Applications

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    Retico, A., Stara, R., Fantacci, M. E., Toncelli, A., Galante, A., Florio, T. M., Alecci, M., Cosottini, M., Astrea, G., Battini, R., Tiberi, G., Costagli, M., & Tosetti, M. (2015). Non-invasive assessment of Neuromuscular Disorders by 7 tesla Magnetic Resonance Imaging and Spectroscopy: Dedicated radio-frequency coil development. In 2015 IEEE International Symposium on Medical Measurements and Applications, MeMeA 2015 - Proceedings (pp. 68-73). [7145174] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/MeMeA.2015.7145174