Non-invasive brain stimulation, a tool to revert maladaptive plasticity in neuropathic pain

Antonino Naro, Demetrio Milardi, Margherita Russo, Carmen Terranova, Vincenzo Rizzo, Alberto Cacciola, Silvia Marino, Rocco S. Calabro, Angelo Quartarone

Research output: Contribution to journalReview article

Abstract

Neuromodulatory effects of non-invasive brain stimulation (NIBS) have been extensively studied in chronic pain. A hypothetic mechanism of action would be to prevent or revert the ongoing maladaptive plasticity within the pain matrix. In this review, the authors discuss the mechanisms underlying the development of maladaptive plasticity in patients with chronic pain and the putative mechanisms of NIBS in modulating synaptic plasticity in neuropathic pain conditions.

Original languageEnglish
Article number376
JournalFrontiers in Human Neuroscience
Volume10
Issue numberJULY2016
DOIs
Publication statusPublished - Jul 27 2016

Keywords

  • Neuropathic pain
  • NIBS
  • Plasticity
  • TDCS
  • TMS

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Neurology
  • Biological Psychiatry
  • Behavioral Neuroscience
  • Neuropsychology and Physiological Psychology

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