Non-invasive coronary angiography with multislice computed tomography. Technology, methods, preliminary experience and prospects

Egidio Traversi, Giuseppe Bertoli, Giancarlo Barazzoni, Maurizia Baldi, Roberto Tramarin

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The recent technical developments in multislice computed tomography (MSCT), with ECG retro-gated image reconstruction, have elicited great interest in the possibility of accurate non-invasive imaging of the coronary arteries. The latest generation of MSCT systems with 8-16 rows of detectors permits acquisition of the whole cardiac volume during a single 15-20 s breath-hold with a submillimetric definition of the images and an outstanding signal-to-noise ratio. Thus the race which, between MSCT, electron beam computed tomography and cardiac magnetic resonance imaging, can best provide routine and reliable imaging of the coronary arteries in clinical practice has recommenced. Currently available MSCT systems offer different options for both cardiac image acquisition and reconstruction, including multiplanar and curved multiplanar reconstruction, three-dimensional volume rendering, maximum intensity projection, and virtual angioscopy. In our preliminary experience including 176 patients suffering from known or suspected coronary artery disease, MSCT was feasible in 161 (91.5%) and showed a sensitivity of 80.4% and a specificity of 80.3%, with respect to standard coronary angiography, in detecting critical stenosis in coronary arteries and artery or venous bypass grafts. These results correspond to a positive predictive value of 58.6% and a negative predictive value of 92.2%. The true role that MSCT is likely to play in the future in non-invasive coronary imaging is still to be defined. Nevertheless, the huge amount of data obtainable by MSCT along with the rapid technological advances, shorter acquisition times and reconstruction algorithm developments will make the technique stronger, and possible applications are expected not only for non-invasive coronary angiography, but also for cardiac function and myocardial perfusion evaluation, as an all-in-one examination.

Original languageEnglish
Pages (from-to)89-98
Number of pages10
JournalItalian Heart Journal
Volume5
Issue number2
Publication statusPublished - Feb 2004

Fingerprint

Multidetector Computed Tomography
Coronary Angiography
Technology
Computer-Assisted Image Processing
Coronary Vessels
Angioscopy
Cardiac Volume
X Ray Computed Tomography
Coronary Stenosis
Signal-To-Noise Ratio
Coronary Artery Disease
Electrocardiography
Arteries
Perfusion
Magnetic Resonance Imaging
Transplants

Keywords

  • Computed tomography
  • Coronary angiography
  • Imaging

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Non-invasive coronary angiography with multislice computed tomography. Technology, methods, preliminary experience and prospects. / Traversi, Egidio; Bertoli, Giuseppe; Barazzoni, Giancarlo; Baldi, Maurizia; Tramarin, Roberto.

In: Italian Heart Journal, Vol. 5, No. 2, 02.2004, p. 89-98.

Research output: Contribution to journalArticle

@article{cb39b78438614ad29eb6d6dbeeb3390a,
title = "Non-invasive coronary angiography with multislice computed tomography. Technology, methods, preliminary experience and prospects",
abstract = "The recent technical developments in multislice computed tomography (MSCT), with ECG retro-gated image reconstruction, have elicited great interest in the possibility of accurate non-invasive imaging of the coronary arteries. The latest generation of MSCT systems with 8-16 rows of detectors permits acquisition of the whole cardiac volume during a single 15-20 s breath-hold with a submillimetric definition of the images and an outstanding signal-to-noise ratio. Thus the race which, between MSCT, electron beam computed tomography and cardiac magnetic resonance imaging, can best provide routine and reliable imaging of the coronary arteries in clinical practice has recommenced. Currently available MSCT systems offer different options for both cardiac image acquisition and reconstruction, including multiplanar and curved multiplanar reconstruction, three-dimensional volume rendering, maximum intensity projection, and virtual angioscopy. In our preliminary experience including 176 patients suffering from known or suspected coronary artery disease, MSCT was feasible in 161 (91.5{\%}) and showed a sensitivity of 80.4{\%} and a specificity of 80.3{\%}, with respect to standard coronary angiography, in detecting critical stenosis in coronary arteries and artery or venous bypass grafts. These results correspond to a positive predictive value of 58.6{\%} and a negative predictive value of 92.2{\%}. The true role that MSCT is likely to play in the future in non-invasive coronary imaging is still to be defined. Nevertheless, the huge amount of data obtainable by MSCT along with the rapid technological advances, shorter acquisition times and reconstruction algorithm developments will make the technique stronger, and possible applications are expected not only for non-invasive coronary angiography, but also for cardiac function and myocardial perfusion evaluation, as an all-in-one examination.",
keywords = "Computed tomography, Coronary angiography, Imaging",
author = "Egidio Traversi and Giuseppe Bertoli and Giancarlo Barazzoni and Maurizia Baldi and Roberto Tramarin",
year = "2004",
month = "2",
language = "English",
volume = "5",
pages = "89--98",
journal = "Italian Heart Journal",
issn = "1129-471X",
publisher = "Societa Italiana di Cardiologia",
number = "2",

}

TY - JOUR

T1 - Non-invasive coronary angiography with multislice computed tomography. Technology, methods, preliminary experience and prospects

AU - Traversi, Egidio

AU - Bertoli, Giuseppe

AU - Barazzoni, Giancarlo

AU - Baldi, Maurizia

AU - Tramarin, Roberto

PY - 2004/2

Y1 - 2004/2

N2 - The recent technical developments in multislice computed tomography (MSCT), with ECG retro-gated image reconstruction, have elicited great interest in the possibility of accurate non-invasive imaging of the coronary arteries. The latest generation of MSCT systems with 8-16 rows of detectors permits acquisition of the whole cardiac volume during a single 15-20 s breath-hold with a submillimetric definition of the images and an outstanding signal-to-noise ratio. Thus the race which, between MSCT, electron beam computed tomography and cardiac magnetic resonance imaging, can best provide routine and reliable imaging of the coronary arteries in clinical practice has recommenced. Currently available MSCT systems offer different options for both cardiac image acquisition and reconstruction, including multiplanar and curved multiplanar reconstruction, three-dimensional volume rendering, maximum intensity projection, and virtual angioscopy. In our preliminary experience including 176 patients suffering from known or suspected coronary artery disease, MSCT was feasible in 161 (91.5%) and showed a sensitivity of 80.4% and a specificity of 80.3%, with respect to standard coronary angiography, in detecting critical stenosis in coronary arteries and artery or venous bypass grafts. These results correspond to a positive predictive value of 58.6% and a negative predictive value of 92.2%. The true role that MSCT is likely to play in the future in non-invasive coronary imaging is still to be defined. Nevertheless, the huge amount of data obtainable by MSCT along with the rapid technological advances, shorter acquisition times and reconstruction algorithm developments will make the technique stronger, and possible applications are expected not only for non-invasive coronary angiography, but also for cardiac function and myocardial perfusion evaluation, as an all-in-one examination.

AB - The recent technical developments in multislice computed tomography (MSCT), with ECG retro-gated image reconstruction, have elicited great interest in the possibility of accurate non-invasive imaging of the coronary arteries. The latest generation of MSCT systems with 8-16 rows of detectors permits acquisition of the whole cardiac volume during a single 15-20 s breath-hold with a submillimetric definition of the images and an outstanding signal-to-noise ratio. Thus the race which, between MSCT, electron beam computed tomography and cardiac magnetic resonance imaging, can best provide routine and reliable imaging of the coronary arteries in clinical practice has recommenced. Currently available MSCT systems offer different options for both cardiac image acquisition and reconstruction, including multiplanar and curved multiplanar reconstruction, three-dimensional volume rendering, maximum intensity projection, and virtual angioscopy. In our preliminary experience including 176 patients suffering from known or suspected coronary artery disease, MSCT was feasible in 161 (91.5%) and showed a sensitivity of 80.4% and a specificity of 80.3%, with respect to standard coronary angiography, in detecting critical stenosis in coronary arteries and artery or venous bypass grafts. These results correspond to a positive predictive value of 58.6% and a negative predictive value of 92.2%. The true role that MSCT is likely to play in the future in non-invasive coronary imaging is still to be defined. Nevertheless, the huge amount of data obtainable by MSCT along with the rapid technological advances, shorter acquisition times and reconstruction algorithm developments will make the technique stronger, and possible applications are expected not only for non-invasive coronary angiography, but also for cardiac function and myocardial perfusion evaluation, as an all-in-one examination.

KW - Computed tomography

KW - Coronary angiography

KW - Imaging

UR - http://www.scopus.com/inward/record.url?scp=4644350529&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=4644350529&partnerID=8YFLogxK

M3 - Article

VL - 5

SP - 89

EP - 98

JO - Italian Heart Journal

JF - Italian Heart Journal

SN - 1129-471X

IS - 2

ER -