Non-invasive stratification of hepatocellular carcinoma risk in non-alcoholic fatty liver using polygenic risk scores

C. Bianco, O. Jamialahmadi, S. Pelusi, G. Baselli, P. Dongiovanni, I. Zanoni, L. Santoro, S. Maier, A. Liguori, M. Meroni, V. Borroni, R. D'Ambrosio, R. Spagnuolo, A. Alisi, A. Federico, E. Bugianesi, S. Petta, L. Miele, U. Vespasiani-Gentilucci, Q.M. AnsteeF. Stickel, J. Hampe, J. Fischer, T. Berg, A.L. Fracanzani, G. Soardo, H. Reeves, D. Prati, S. Romeo, L. Valenti

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)775-782
Number of pages8
JournalJournal of Hepatology
Volume74
Issue number4
DOIs
Publication statusPublished - 2021

Keywords

  • Biomarker
  • Cirrhosis
  • Genetics
  • Hepatic fat
  • Non-alcoholic fatty liver disease
  • glucokinase regulator
  • liver protein
  • membrane bound o acyltransferase domain containing 7
  • patatin like phospholipase domain containing protein 3
  • transmembrane 6 superfamily member 2
  • unclassified drug
  • adult
  • aged
  • Article
  • cancer diagnosis
  • cancer patient
  • cancer risk
  • cancer susceptibility
  • case control study
  • cohort analysis
  • controlled study
  • cross-sectional study
  • diagnostic accuracy
  • diagnostic test accuracy study
  • disease association
  • female
  • follow up
  • genetic association
  • genetic predisposition
  • genetic risk
  • genetic risk score
  • genetic susceptibility
  • genetic variability
  • German (citizen)
  • hospital based case control study
  • human
  • liver cell carcinoma
  • liver cirrhosis
  • liver fibrosis
  • major clinical study
  • male
  • nonalcoholic fatty liver
  • obesity
  • predictive value
  • priority journal
  • receiver operating characteristic
  • sensitivity and specificity

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