Non-invasive vulnerable plaque imaging: how do we know that treatment works?

Anna Sannino, Linda Brevetti, Giuseppe Giugliano, Fernando Scudiero, Evelina Toscano, Ciro Mainolfi, Alberto Cuocolo, Cinzia Perrino, Eugenio Stabile, Bruno Trimarco, Giovanni Esposito

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Atherosclerosis is an inflammatory disorder that can evolve into an acute clinical event by plaque development, rupture, and thrombosis. Plaque vulnerability represents the susceptibility of a plaque to rupture and to result in an acute cardiovascular event. Nevertheless, plaque vulnerability is not an established medical diagnosis, but rather an evolving concept that has gained attention to improve risk prediction. The availability of high-resolution imaging modalities has significantly facilitated the possibility of performing in vivo regression studies and documenting serial changes in plaque stability. This review summarizes the currently available non-invasive methods to identify vulnerable plaques and to evaluate the effects of the current cardiovascular treatments on plaque evolution.

Original languageEnglish
Pages (from-to)1194-1202
Number of pages9
JournalEuropean Heart Journal Cardiovascular Imaging
Volume15
Issue number11
DOIs
Publication statusPublished - Nov 1 2014

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Rupture
Atherosclerosis
Thrombosis

Keywords

  • Atherosclerosis
  • Cardiovascular risk
  • Cardiovascular treatment
  • Non-invasive imaging
  • Vulnerable plaque

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Sannino, A., Brevetti, L., Giugliano, G., Scudiero, F., Toscano, E., Mainolfi, C., ... Esposito, G. (2014). Non-invasive vulnerable plaque imaging: how do we know that treatment works? European Heart Journal Cardiovascular Imaging, 15(11), 1194-1202. https://doi.org/10.1093/ehjci/jeu097

Non-invasive vulnerable plaque imaging : how do we know that treatment works? / Sannino, Anna; Brevetti, Linda; Giugliano, Giuseppe; Scudiero, Fernando; Toscano, Evelina; Mainolfi, Ciro; Cuocolo, Alberto; Perrino, Cinzia; Stabile, Eugenio; Trimarco, Bruno; Esposito, Giovanni.

In: European Heart Journal Cardiovascular Imaging, Vol. 15, No. 11, 01.11.2014, p. 1194-1202.

Research output: Contribution to journalArticle

Sannino, A, Brevetti, L, Giugliano, G, Scudiero, F, Toscano, E, Mainolfi, C, Cuocolo, A, Perrino, C, Stabile, E, Trimarco, B & Esposito, G 2014, 'Non-invasive vulnerable plaque imaging: how do we know that treatment works?', European Heart Journal Cardiovascular Imaging, vol. 15, no. 11, pp. 1194-1202. https://doi.org/10.1093/ehjci/jeu097
Sannino A, Brevetti L, Giugliano G, Scudiero F, Toscano E, Mainolfi C et al. Non-invasive vulnerable plaque imaging: how do we know that treatment works? European Heart Journal Cardiovascular Imaging. 2014 Nov 1;15(11):1194-1202. https://doi.org/10.1093/ehjci/jeu097
Sannino, Anna ; Brevetti, Linda ; Giugliano, Giuseppe ; Scudiero, Fernando ; Toscano, Evelina ; Mainolfi, Ciro ; Cuocolo, Alberto ; Perrino, Cinzia ; Stabile, Eugenio ; Trimarco, Bruno ; Esposito, Giovanni. / Non-invasive vulnerable plaque imaging : how do we know that treatment works?. In: European Heart Journal Cardiovascular Imaging. 2014 ; Vol. 15, No. 11. pp. 1194-1202.
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