TY - JOUR
T1 - Non-palpable thyroid nodules in a borderline iodine-sufficient area
T2 - Detection by ultrasonography and follow-up
AU - Rago, T.
AU - Chiovato, L.
AU - Aghini-Lombardi, F.
AU - Grasso, L.
AU - Pinchera, A.
AU - Vitti, P.
PY - 2001
Y1 - 2001
N2 - Thyroid ultrasonography was performed in 482 subjects, free of known thyroid disease and living in a borderline iodine-sufficient urban area, to assess the prevalence of non-palpable thyroid nodules and evaluation their evolute during a 3-yr follow-up. The mean (±SD) thyroid volume in the whole study group was 10.9±3.7 ml and was higher in males (12.9±3.6 ml) than in females (9.2±2.9 ml) (p2=10.21; p=0.001). Multiple nodules were found in 3/464 subjects (0.6%) with a thyroid of normal volume and in 3/18 (16.6%) subjects with goiter (x2=24.31; p35 yr than in those 2=7.47; p=0.0062). A significant increase (>30%) of nodular volume was found in 5 subjects, while an increased number of nodules was found in 8. In conclusion, thyroid ultrasonography reveals the presence of thyroid nodules in a significant proportion of apparently thyroid disease-free subjects living in a borderline iodine-sufficient urban area. Incidentally discovered thyroid nodules are associated with goiter and are likely to progress in volume and number.
AB - Thyroid ultrasonography was performed in 482 subjects, free of known thyroid disease and living in a borderline iodine-sufficient urban area, to assess the prevalence of non-palpable thyroid nodules and evaluation their evolute during a 3-yr follow-up. The mean (±SD) thyroid volume in the whole study group was 10.9±3.7 ml and was higher in males (12.9±3.6 ml) than in females (9.2±2.9 ml) (p2=10.21; p=0.001). Multiple nodules were found in 3/464 subjects (0.6%) with a thyroid of normal volume and in 3/18 (16.6%) subjects with goiter (x2=24.31; p35 yr than in those 2=7.47; p=0.0062). A significant increase (>30%) of nodular volume was found in 5 subjects, while an increased number of nodules was found in 8. In conclusion, thyroid ultrasonography reveals the presence of thyroid nodules in a significant proportion of apparently thyroid disease-free subjects living in a borderline iodine-sufficient urban area. Incidentally discovered thyroid nodules are associated with goiter and are likely to progress in volume and number.
KW - Thyroid nodules
KW - Thyroid ultrasonography
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M3 - Article
C2 - 11765046
AN - SCOPUS:0035202320
VL - 24
SP - 770
EP - 776
JO - Journal of Endocrinological Investigation
JF - Journal of Endocrinological Investigation
SN - 0391-4097
IS - 10
ER -