Non-rash dermatologic adverse events related to targeted therapies

Jane Bryce, Christine B. Boers-Doets

Research output: Contribution to journalArticlepeer-review


Objectives: To provide background information and management strategies for non-rash dermatological adverse events. Data Sources: Peer-reviewed journal articles, professional manuals, online sources. Conclusion: During the last decade, many dermatological adverse events of targeted therapy have been reported, including xerosis, skin fissures, pruritus, photosensitivity, pigmentation changes, hair and nail changes, hand-foot skin reaction, squamoproliferative lesions, Stevens-Johnsons syndrome, and toxic epidermal necrolysis. Although evidenced-based treatment options are scarce, many recommendations have been described in the literature that should be considered to apply in daily practice. Implications for Nursing Practice: Nursing practice will be enhanced by education, assessment, and management recommendations.

Original languageEnglish
Pages (from-to)155-168
Number of pages14
JournalSeminars in Oncology Nursing
Issue number3
Publication statusPublished - 2014


  • Assessment
  • Education
  • Management
  • Non-rash adverse events
  • Targeted therapy

ASJC Scopus subject areas

  • Oncology(nursing)
  • Medicine(all)


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